Long-term atorvastatin improves cognitive function by modulating SIRT2-mediated dynamic transition of NFL lysine 272 crotonylation to ubiquitination in naturally aging rats. [PDF]
Cell Death DiscovXu TC, Cai JR, Chen HS.
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Plasma levels of sirtuin 1 and sirtuin 2 in ascending aortic aneurysm patients - a comparative study. [PDF]
Cardiol JKrekora J +8 more
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An In Vivo Drug Screen Reveals That Sirtuin 2 Activity Promotes Spinal Cord Neurogenesis in Developing Zebrafish. [PDF]
BiomoleculesGonzález-Llera L +3 more
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Lactate orchestrates the TGFβ pathway and ferroptosis nexus in organ fibrosis via USP2 lactylation. [PDF]
Commun BiolXiang J +9 more
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Structural basis of SIRT2 pre-catalysis NAD<sup>+</sup> binding dynamics and mechanism. [PDF]
RSC Chem BiolZhang N, Pow KC, Chen L, Hao Q.
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Lead Structure-Based Hybridization Strategy Reveals Major Potency Enhancement of SirReal-Type Sirt2 Inhibitors. [PDF]
Int J Mol SciFrei M, Wirawan R, Wein T, Bracher F.
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Mechanistic Insights Into Celastrol's Anti-Pyroptosis Effects in Osteoarthritis via SIRT2 Upregulation. [PDF]
Mediators InflammChen X +5 more
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Research progress on sirtuin family genes in colorectal cancer. [PDF]
Front OncolLiu T, Wu T, Luo L, Li W, Zhang M.
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Sirtuins as Therapeutic Targets for Treating Cancer, Metabolic Diseases, and Neurodegenerative Diseases. [PDF]
Pharmaceuticals (Basel)Akantibila M, Carabetta VJ.
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