Results 271 to 280 of about 87,529 (407)

Saccharomyces boulardii modulates necrotizing enterocolitis in neonatal mice by regulating the sirtuin 1/NF‑κB pathway and the intestinal microbiota

, 2020
Kun Zhang, Xi Zhang, Anping Lv, Sainan Fan, Jinping Zhang   +4 more
openalex   +2 more sources

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry, David M. Thompson, Jean‐Pierre Chanoine   +2 more
wiley   +1 more source

Sirtuins as Therapeutic Targets for Treating Cancer, Metabolic Diseases, and Neurodegenerative Diseases. [PDF]

Pharmaceuticals (Basel)
Akantibila M, Carabetta VJ.
europepmc   +1 more source

Persimmon carotenoid extract rich in β‐cryptoxanthin improves glucose homeostasis and reduces liver damage in high‐fat‐diet‐induced type 2 diabetic and metabolic dysfunction‐associated steatotic liver disease mice

Journal of the Science of Food and Agriculture, Volume 106, Issue 2, Page 1299-1313, 30 January 2026.
Abstract Background Persimmon (Diospyros kaki Thunb.) byproducts are a remarkable source of bioactive compounds, particularly carotenoids. Several studies suggest that carotenoids have beneficial effects in prevention of a large number of diseases. This study aims to highlight the effects of a persimmon carotenoid extract (PSCE) rich in β‐cryptoxanthin
Bryan Moreno‐Chamba, Nuria Martí, Antonio Cárdenas, María Soledad Fernández‐Pachón, Blanca Escudero‐López, Franz Martín, Julio Salazar‐Bermeo, Manuel Valero, Domingo Saura, María Concepción Martínez‐Madrid, Genoveva Berná   +10 more
wiley   +1 more source

Elevated Sirtuin 1 Levels in Patients with Chronic Kidney Disease, Including on Peritoneal Dialysis: Associations with Cardiovascular Risk and Peritoneal Fibrosis. [PDF]

Int J Mol Sci
Bielach-Bazyluk A, Czajkowska K, Koc-Zorawska E, Hryszko T, Zbroch E.   +4 more
europepmc   +1 more source

Bioinformatic analyses of metallome and structural analysis of sirtuin from Glaciozyma antarctica PII2 [PDF]

, 2014
Pik Mun Foong
openalex  

Sirtuin 1 Mediates Hydrogen Sulfide-induced Cytoprotection Effects in Neonatal Mouse Cardiomyocytes.

, 2017
Aijun Liu, Bin Li, Ming Yang, Yang Liu, Yinglong Liu, Junwu Su   +5 more
openalex   +1 more source

Dataset related to: Low Nephron Number Induced by Maternal Protein Restriction Is Prevented by Nicotinamide Riboside Supplementation Depending on Sirtuin 3 Activation

, 2022
Anna Pezzotta, Luca Perico, Marina Morigi, Daniela Corna, Monica Locatelli, Carla Zoja, Ariela Benigni, Giuseppe Remuzzi, Barbara Imberti   +8 more
openalex   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

SRT2104 enhances dendritic outgrowth and spine formation through Sirtuin 1-mediated mTORC1 signaling. [PDF]

Sci Rep
Seo MK, Lee JG, Kim JH, Seog DH, Jeong S, Kim SH, Lee JY, Park SW.   +7 more
europepmc   +1 more source