Results 281 to 290 of about 69,505 (315)

Sirtuins, epigenetics and longevity

Ageing Research Reviews, 2017
Aging of organisms begins from a single cell at the molecular level. It includes changes related to telomere shortening, cell senescence and epigenetic modifications. These processes accumulate over the lifespan. Research studies show that epigenetic signaling contributes to human disease, tumorigenesis and aging.
Mateusz, Wątroba, Ilona, Dudek, Marta, Skoda, Aleksandra, Stangret, Przemysław, Rzodkiewicz, Dariusz, Szukiewicz   +5 more
openaire   +2 more sources

Sirtuins

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2010
openaire   +2 more sources

The sirtuin family in health and disease

Signal Transduction and Targeted Therapy, 2022

exaly  

Sirtuin

2016
Xiaogang Chu, Ryan George, Raghavan Raju
openaire   +1 more source

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

Nature Reviews Molecular Cell Biology, 2016
Michael S Bonkowski, David A Sinclair
exaly  

Sirtuins

RCSB Protein Data Bank, 2017
openaire   +1 more source

Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease

Science, 2007
Tiago Fleming Outeiro, Irina Kufareva, Jean-Christophe Rochet   +2 more
exaly  

Therapeutic potential of resveratrol: the in vivo evidence

Nature Reviews Drug Discovery, 2006
Joseph A Baur, David A Sinclair
exaly  

Regulation of Hypoxia-Inducible Factor 2α Signaling by the Stress-Responsive Deacetylase Sirtuin 1

Science, 2009
Matthew S Alexander, Joseph A Garcia
exaly  

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

Nature Reviews Molecular Cell Biology, 2008
Xiang-Jiao Yang, Edward Seto
exaly