Results 31 to 40 of about 23,914,328 (286)
Role of acetylation in nonalcoholic fatty liver disease: a focus on SIRT1 and SIRT3
Exploration of Medicine, 2020 Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent liver chronic disease worldwide. The pathogenesis of NAFLD is complex and involves many metabolic enzymes and multiple pathways.
Fatiha Nassir
doaj +1 more source
The role of Sirtuin 1 in the pathophysiology of polycystic ovary syndrome
European Journal of Medical Research, 2022 Polycystic ovarian syndrome (PCOS) is the most common multifactor heterogeneous endocrine and metabolic disease in women of childbearing age. PCOS is a group of clinical syndromes characterized by reproductive disorders, metabolic disorders, and mental ...
Mali Wu +9 more
semanticscholar +1 more source
(+)-Catechin & Proanthocyanidin Fraction of Uncaria gambir Roxb. Improve Adipocytes Differentiation & Glucose Uptake of 3T3-L1 Cells Via Sirtuin-1, Peroxisome Proliferator-Activated Receptor γ (PPAR γ), Glucose Transporter Type 4 (GLUT-4) Expressions [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: To improve adipocytes differentiation & glucose uptake activity of 3T3-L1 cells through sirtuin-1, peroxisome proliferator-activated receptor γ (PPAR γ), glucose transporter type 4 (GLUT-4) of (+)-catechin & proanthocyanidin fraction Uncaria ...
Silvy Arundita +3 more
doaj +1 more source
Decreased Serum Sirtuin-1 in COPD [PDF]
Chest, 2017 The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD.Serum SIRT1 protein of all samples was measured by Western blot, and the SIRT1 protein band ...
Yanagisawa, S +7 more
openaire +4 more sources
Phospholipase D2 is a positive regulator of sirtuin 1 and modulates p53-mediated apoptosis via sirtuin 1 [PDF]
Experimental & Molecular Medicine, 2021 AbstractSirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent histone deacetylase that plays diverse physiological roles. However, little is known about the regulation of SIRT1 activity. Here, we show that phospholipase D2 (PLD2), but not PLD1, selectively interacts with SIRT1 and increases the deacetylase activity of SIRT1.
Taek-Yeol Jung +5 more
openaire +3 more sources
Biomedicines, 2021 The signaling pathways involved in age-related inflammation are increasingly recognized as targets for the development of preventive and therapeutic strategies.
Cátia Sousa +3 more
doaj +1 more source
Journal of Clinical Medicine, 2022 Background: Coffee is one of the most popular beverages globally and contains several bioactive compounds that are relevant to human health. Many nutritional strategies modulate sirtuin-1, thereby impacting aging and cardiometabolic health.
Gustavo Henrique Ferreira Gonçalinho +7 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 HSV-1 is a typical neurotropic virus that infects the brain and causes keratitis, cold sores, and occasionally, acute herpes simplex encephalitis (HSE).
Xiaowei Song +10 more
semanticscholar +1 more source
Jurnal Kesehatan Andalas, 2023 Mesenchymal Stem Cells Wharton's Jelly (MSC-WJ) has become a new hope for Alzheimer's disease due to its capability to suppress Amyloid-beta (Aβ) plaques formation.
Havina Nurul Aizah +5 more
doaj +1 more source
Journal of International Medical Research, 2020 Objectives A relationship exists between sirtuin-1 expression and growth and survival of malignant tumors. This study aimed to investigate the prognostic value of sirtuin-1 and vascular endothelial growth factor (VEGF) expression in patients with ...
Hongzeng Wu +7 more
doaj +1 more source