Results 151 to 160 of about 17,907 (258)

Correction: Zgutka et al. Sirtuins and Their Implications in the Physiopathology of Gestational Diabetes Mellitus. <i>Pharmaceuticals</i> 2025, <i>18</i>, 41. [PDF]

Pharmaceuticals (Basel)
Zgutka K, Tkacz M, Grabowska M, Mikołajek-Bedner W, Tarnowski M.   +4 more
europepmc   +1 more source

Tocotrienols: A Review From Source to Therapeutic Applications

Food Frontiers, Volume 7, Issue 2, March 2026.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño, Nidia Casas‐Forero, Andres‐Felipe Garzón‐Méndez, Dalí‐Aleixandra Rojas‐Díaz, Mary‐Luz Olivares‐Tenorio, Hernan‐Mauricio Romero, Jesús‐Alberto García‐Núñez   +6 more
wiley   +1 more source

Exercise and the hepatic sirtuin network: rethinking the research focus on SIRT1, SIRT3, and SIRT6. [PDF]

Front Physiol
Kwon JW.
europepmc   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

Plasma levels of sirtuin 1 and sirtuin 2 in ascending aortic aneurysm patients - a comparative study. [PDF]

Cardiol J
Krekora J, Matuszewska-Brycht O, Fryczak J, Stępiński P, Krejca M, Siejka A, Kaczmarek D, Merks P, Drożdż J.   +8 more
europepmc   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Traditional Health Practices May Promote Nrf2 Activation Similar to Exercise. [PDF]

Int J Mol Sci
Kolb H, Martin S, Kempf K.
europepmc   +1 more source

Nutrigenomics of the Mediterranean Diet: Gene–Diet Interactions and Bioactive Compounds in Cardiovascular Health

Food Frontiers, Volume 7, Issue 2, March 2026.
The Mediterranean diet interacts with genetic and epigenetic backgrounds to modulate nutrigenomic mechanisms, including DNA methylation, histone modification and microRNA regulation. These molecular effects reduce inflammation and oxidative stress, enhance nitric oxide bioavailability and lipid metabolism and translate into improved cardiometabolic ...
Karina Ramírez‐Alarcón, Ana María Labraña, Fernanda Carrasco‐Marín, Pilar Benítez‐Cid, Rafael Zapata‐Lamana, Xavier Capó, Margalida Monserrat‐Mesquida, Antoni Sureda, Héctor Contreras, Francisca Valenzuela‐Mella, Daniel Pacheco Bravo, Daniela Calina, Maria de la Luz Cádiz‐Gurrea, Antonio Segura‐Carretero, William N. Setzer, Javad Sharifi‐Rad, Miquel Martorell   +16 more
wiley   +1 more source

Deacetylation of SOD3 by sirtuins restores furin cleavage. [PDF]

Redox Biochem Chem
Mitchem EC, Harris PS, Michel CR, McGinnis CD, Ray S, Mallela KMG, Roede JR, Petersen SV, Nozik ES, Fritz KS.   +9 more
europepmc   +1 more source

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie, Abdelghafar Abu‐Elsaoud   +1 more
wiley   +1 more source