Mechanics of Sister Chromatids studied with a Polymer Model
Frontiers in Physics, 2013 Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells.
Yang eZhang +3 more
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Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.
, 2020 In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U. +6 more
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Establishment of Sister Chromatid Cohesion [PDF]
Current Biology, 2009 The process of sister chromatid pairing, or cohesion establishment, is coupled to DNA replication and fundamental to proper chromosome segregation and cell viability. In the past year, several articles have provided important new insights into cohesion establishment, an activity predicated on the acetyltransferase Ctf7/Eco1. Here, I review new findings
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PHB2 Protects Sister-Chromatid Cohesion in Mitosis [PDF]
Current Biology, 2007 Cohesion between sister chromatids is essential for proper chromosome segregation in mitosis. In vertebrate mitotic cells, most cohesin is removed from the chromosome arms [1-4], but centromeric cohesin is protected by shugoshin until the onset of anaphase [5].
Takata, Hideaki +9 more
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Function and mechanism of cohesin REC8 during meiosis
浙江大学学报. 农业与生命科学版, 2023 Cohesin is a functionally and evolutionarily conserved multi-subunit protein complex that is required for sister chromatid cohesion and chromatin loop structure in both mitosis and meiosis. The meiotic cell-cycle consisting of one DNA replication and two
DAI Jingling, YU Chao
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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]
, 2007 Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Gruneberg, Ulrike +3 more
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The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. [PDF]
PLoS Genetics, 2010 The DNA replication process represents a source of DNA stress that causes potentially spontaneous genome damage. This effect might be strengthened by mutations in crucial replication factors, requiring the activation of DNA damage checkpoints to enable ...
Naoki Takahashi +9 more
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How to halve ploidy : lessons from budding yeast meiosis [PDF]
, 2012 Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash +2 more
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Pericentromeric Sister Chromatid Cohesion Promotes Kinetochore Biorientation [PDF]
Molecular Biology of the Cell, 2009 Accurate chromosome segregation depends on sister kinetochores making bioriented attachments to microtubules from opposite poles. An essential regulator of biorientation is the Ipl1/Aurora B protein kinase that destabilizes improper microtubule–kinetochore attachments.
Tessie M, Ng +3 more
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Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2013 The conserved family of cohesin proteins that mediate sister chromatid cohesion requires Scc2, Scc4 for chromatin-association and Eco1/Ctf7 for conversion to a tethering competent state.
Soumya Rudra, Robert V Skibbens
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