Results 61 to 70 of about 11,947 (194)
Homologous recombination, sister chromatid cohesion, and chromosome condensation in mammalian meiosis [PDF]
, 2002 In the life cycle of sexually reproducing eukaryotes, haploid and diploid generations of cells alternate. Two types of cell division occur in such a life cycle: mitosis and meiosis. They are compared in chapter 1 .
Eijpe, M.
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Manipulating sister chromatid cohesion to prevent aneuploidy [PDF]
Oocyte aneuploidy has been shown to be one of the major causes of age-dependent aneuploidy which can lead to trisomic pregnancies, miscarriages and an overall decrease in fertility rates.
Muñoz Grande, Alba
core +1 more source
The interplay of cohesin and DNA replication in sister chromatid cohesion [PDF]
, 2023 In order to duplicate, cells need to faithfully replicate their DNA followed by the coordinated transfer of duplicated chromosomes to the future daughter cells.
van Schie, Janne Jo Minne
core +1 more source
Cell Reports, 2015 Sister chromatid cohesion, mediated by the cohesin complex, is essential for faithful mitosis. Nevertheless, evidence suggests that the surveillance mechanism that governs mitotic fidelity, the spindle assembly checkpoint (SAC), is not robust enough to ...
Mihailo Mirkovic +3 more
doaj +1 more source
The cohesion protein SOLO associates with SMC1 and is required for synapsis, recombination, homolog bias and cohesion and pairing of centromeres in Drosophila Meiosis. [PDF]
PLoS Genetics, 2013 Cohesion between sister chromatids is mediated by cohesin and is essential for proper meiotic segregation of both sister chromatids and homologs. solo encodes a Drosophila meiosis-specific cohesion protein with no apparent sequence homology to cohesins ...
Rihui Yan, Bruce D McKee
doaj +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Replication factor C complexes play unique pro- and anti-establishment roles in sister chromatid cohesion. [PDF]
PLoS ONE, 2010 Recent studies have lead to a rapid expansion of sister chromatid cohesion pathways. Of particular interest is the growth in classifications of anti-establishment factors-now including those that are cohesin-associated (Rad61/WAPL and Pds5) or DNA ...
Marie E Maradeo, Robert V Skibbens
doaj +1 more source
Advanced Science, EarlyView.A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan +24 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source