Results 41 to 50 of about 10,437 (162)
Function and mechanism of cohesin REC8 during meiosis
浙江大学学报. 农业与生命科学版, 2023 Cohesin is a functionally and evolutionarily conserved multi-subunit protein complex that is required for sister chromatid cohesion and chromatin loop structure in both mitosis and meiosis. The meiotic cell-cycle consisting of one DNA replication and two
DAI Jingling, YU Chao
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In Favor of Establishment: Regulation of Chromatid Cohesion in Plants
Frontiers in Plant Science, 2017 In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes into daughter cells during ...
Pablo Bolaños-Villegas +4 more
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The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. [PDF]
PLoS Genetics, 2010 The DNA replication process represents a source of DNA stress that causes potentially spontaneous genome damage. This effect might be strengthened by mutations in crucial replication factors, requiring the activation of DNA damage checkpoints to enable ...
Naoki Takahashi +9 more
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Sister Chromatid Cohesion Remodeling and Meiotic Recombination [PDF]
Cell Cycle, 2006 Proper control of cohesion along the chromosome arms is essential for segregation of homologous chromosomes in meiosis. In a recent study we reported that Tid1p, a protein previously implicated in recombination, is required for resolution of Mcd1p-dependent cohesion in meiosis. Here we demonstrate that Pds5p and Dmc1p promote this cohesion.
Anna V, Kateneva, Michael E, Dresser
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A Physical Assay for Sister Chromatid Cohesion In Vitro [PDF]
Molecular Cell, 2007 Cohesion between sister chromatids depends on a multiprotein complex called cohesin that has been proposed to hold sister DNAs together by trapping them inside a large tripartite ring. Sister chromatid cohesion has hitherto only been detected by using cytological methods in living cells.
Ivanov, D, Nasmyth, K
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Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes
eLife, 2021 Cohesin’s association with and translocation along chromosomal DNAs depend on an ATP hydrolysis cycle driving the association and subsequent release of DNA. This involves DNA being ‘clamped’ by Scc2 and ATP-dependent engagement of cohesin’s Smc1 and Smc3
Naomi J Petela +13 more
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Sequential loading of cohesin subunits during the first meiotic prophase of grasshoppers.
PLoS Genetics, 2007 The cohesin complexes play a key role in chromosome segregation during both mitosis and meiosis. They establish sister chromatid cohesion between duplicating DNA molecules during S-phase, but they also have an important role during postreplicative double-
Ana M Valdeolmillos +10 more
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Sororin actively maintains sister chromatid cohesion. [PDF]
EMBO J, 2016 Cohesion between sister chromatids is established during DNA replication but needs to be maintained to enable proper chromosome-spindle attachments in mitosis or meiosis. Cohesion is mediated by cohesin, but also depends on cohesin acetylation and sororin. Sororin contributes to cohesion by stabilizing cohesin on DNA.
Ladurner R +8 more
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A Live-Cell Imaging Approach for Measuring DNA Replication Rates
Cell Reports, 2018 Summary: We describe a simple and direct approach to measure the progression of single DNA replication forks in living cells by monitoring two fluorescently labeled loci downstream of an origin of replication.
Daniel Dovrat +5 more
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The Making and Breaking of Sister Chromatid Cohesion [PDF]
Cell, 2001 The picture that emerges from recent studies is that of an intricate regulatory network, the purpose of which is to ensure that sister chromatids go their separate ways during anaphase. The more we know about the process, the more challenging our next questions become.
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