Results 31 to 40 of about 11,947 (194)
Chromatid Cohesion: Acetylation Joins the Sisters [PDF]
Current Biology, 2008 The replication-fork-associated protein Eco1 is required for the establishment of sister chromatid cohesion, which plays an essential role in faithful chromosome segregation. Three recent studies in yeast and humans reveal that the acetyltransferase activity of Eco1 targets the cohesin subunit Smc3 to facilitate the establishment of cohesion.
Tanaka, Koichi, Watanabe, Yoshinori
openaire +2 more sources
eLife, 2022 Cohesin organizes the genome by forming intra-chromosomal loops and inter-sister chromatid linkages. During gamete formation by meiosis, chromosomes are reshaped to support crossover recombination and two consecutive rounds of chromosome segregation ...
Rachael E Barton +3 more
doaj +1 more source
Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase [PDF]
, 2014 Two mechanisms safeguard the bipolar attachment of chromosomes in mitosis. A correction mechanism destabilizes erroneous attachments that do not generate tension across sister kinetochores [1].
Vázquez-Novelle, María Dolores +6 more
core +1 more source
Rtt101‐Mms1‐Mms22 coordinates replication‐coupled sister chromatid cohesion and nucleosome assembly [PDF]
EMBO Reports, 2017 Cong Liu, , Jun Tang
exaly +2 more sources
The cohesin ring concatenates sister DNA molecules [PDF]
, 2008 Sister chromatid cohesion, which is essential for mitosis, is mediated by a multi-subunit protein complex called cohesin whose Scc1, Smc1, and Smc3 subunits form a tripartite ring structure.
Arumugam, P +9 more
core +1 more source
Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2
Life Science Alliance, 2020 This study reveals a role for the cohesin modifier ESCO2 for maintenance of sister chromatid cohesion in mammalian meiosis and a specific weakness of cohesion within male sex chromosome chromatin In mitotic cells, establishment of sister chromatid ...
François McNicoll +6 more
doaj +1 more source
Genome Biology, 2022 Background Cohesin is a chromosome-associated SMC–kleisin complex that mediates sister chromatid cohesion, recombination, and most chromosomal processes during mitosis and meiosis.
Eui-Hwan Choi +7 more
doaj +1 more source
Handcuff for sisters: A new model for sister chromatid cohesion [PDF]
Cell Cycle, 2009 High fidelity chromosome transmission requires the pairing of sister chromatids by a group of conserved proteins called cohesins during S-phase. Sister chromatid cohesion is maintained until anaphase onset. Presently, there are two sets of models of cohesin complex popular in the cohesin biology field: one model predicts that single cohesin rings ...
Nenggang, Zhang, Debananda, Pati
openaire +2 more sources
PLoS Biology, 2012 Successful execution of the meiotic program depends on the timely establishment and removal of sister chromatid cohesion. LAB-1 has been proposed to act in the latter by preventing the premature removal of the meiosis-specific cohesin REC-8 at metaphase ...
Yonatan B Tzur +7 more
doaj +1 more source
Mechanics of Sister Chromatids studied with a Polymer Model
Frontiers in Physics, 2013 Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells.
Yang eZhang +3 more
doaj +1 more source