Results 31 to 40 of about 10,437 (162)
Chromatid Cohesion: Acetylation Joins the Sisters [PDF]
Current Biology, 2008 The replication-fork-associated protein Eco1 is required for the establishment of sister chromatid cohesion, which plays an essential role in faithful chromosome segregation. Three recent studies in yeast and humans reveal that the acetyltransferase activity of Eco1 targets the cohesin subunit Smc3 to facilitate the establishment of cohesion.
Tanaka, Koichi, Watanabe, Yoshinori
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eLife, 2022 Cohesin organizes the genome by forming intra-chromosomal loops and inter-sister chromatid linkages. During gamete formation by meiosis, chromosomes are reshaped to support crossover recombination and two consecutive rounds of chromosome segregation ...
Rachael E Barton +3 more
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Rtt101‐Mms1‐Mms22 coordinates replication‐coupled sister chromatid cohesion and nucleosome assembly [PDF]
EMBO Reports, 2017 Jun Tang +2 more
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Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2
Life Science Alliance, 2020 This study reveals a role for the cohesin modifier ESCO2 for maintenance of sister chromatid cohesion in mammalian meiosis and a specific weakness of cohesion within male sex chromosome chromatin In mitotic cells, establishment of sister chromatid ...
François McNicoll +6 more
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Genome Biology, 2022 Background Cohesin is a chromosome-associated SMC–kleisin complex that mediates sister chromatid cohesion, recombination, and most chromosomal processes during mitosis and meiosis.
Eui-Hwan Choi +7 more
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Establishment of Sister Chromatid Cohesion [PDF]
Current Biology, 2009 The process of sister chromatid pairing, or cohesion establishment, is coupled to DNA replication and fundamental to proper chromosome segregation and cell viability. In the past year, several articles have provided important new insights into cohesion establishment, an activity predicated on the acetyltransferase Ctf7/Eco1. Here, I review new findings
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Handcuff for sisters: A new model for sister chromatid cohesion [PDF]
Cell Cycle, 2009 High fidelity chromosome transmission requires the pairing of sister chromatids by a group of conserved proteins called cohesins during S-phase. Sister chromatid cohesion is maintained until anaphase onset. Presently, there are two sets of models of cohesin complex popular in the cohesin biology field: one model predicts that single cohesin rings ...
Nenggang, Zhang, Debananda, Pati
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Mechanics of Sister Chromatids studied with a Polymer Model
Frontiers in Physics, 2013 Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells.
Yang eZhang +3 more
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PLoS Biology, 2012 Successful execution of the meiotic program depends on the timely establishment and removal of sister chromatid cohesion. LAB-1 has been proposed to act in the latter by preventing the premature removal of the meiosis-specific cohesin REC-8 at metaphase ...
Yonatan B Tzur +7 more
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Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function.
PLoS Genetics, 2018 The cohesin complex topologically encircles chromosomes and mediates sister chromatid cohesion to ensure accurate chromosome segregation upon cell division. Cohesin also participates in DNA repair and gene transcription. The Nipped-B-Mau2 protein complex
Ziva Misulovin +3 more
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