Results 11 to 20 of about 921,868 (189)

Sister chromatid cohesion [PDF]

Cold Spring Harbor Perspectives in Biology, 2012
During S phase, not only does DNA have to be replicated, but also newly synthesized DNA molecules have to be connected with each other. This sister chromatid cohesion is essential for the biorientation of chromosomes on the mitotic or meiotic spindle ...
Jan-michael Peters, Tomoko Nishiyama
core   +7 more sources

Establishment of Sister Chromatid Cohesion [PDF]

Current Biology, 2009
The process of sister chromatid pairing, or cohesion establishment, is coupled to DNA replication and fundamental to proper chromosome segregation and cell viability.
Robert V. Skibbens, Skibbens, Robert V.
core   +4 more sources

Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication [PDF]

Molecular Cell
Concomitant with DNA replication, the ring-shaped cohesin complex encircles both newly synthesized sister chromatids, enabling their faithful segregation during cell divisions.
John Diffley, Frank Uhlmann, Masashi Minamino   +2 more
exaly   +3 more sources

Targeted sister chromatid cohesion by Sir2.

PLoS Genetics, 2011
The protein complex known as cohesin binds pericentric regions and other sites of eukaryotic genomes to mediate cohesion of sister chromatids. In budding yeast Saccharomyces cerevisiae, cohesin also binds silent chromatin, a repressive chromatin ...
Ching-Shyi Wu, Yu-Fan Chen, Marc R Gartenberg   +2 more
doaj   +3 more sources

Sister chromatid cohesion and recombination in meiosis

Chromosoma, 2000
Sister chromatids are associated from their formation until their disjunction. Cohesion between sister chromatids is provided by protein complexes, of which some components are conserved across the kingdoms and between the mitotic and meiotic cell cycles.
Heemst, D., van, van Heemst, D., Heyting, C.   +2 more
core   +3 more sources

Cohesin: Functions beyond sister chromatid cohesion [PDF]

FEBS Letters, 2013
Faithful segregation of chromosomes during mitosis and meiosis is the cornerstone process of life. Cohesin, a multi-protein complex conserved from yeast to human, plays a crucial role in this process by keeping the sister chromatids together from S-phase
Mehta, Gunjan D., Kumar, Ravinder, Srivastava, Sanjeeva, Ghosh, Santanu Kumar   +3 more
core   +4 more sources

Sister Chromatid Cohesion Control and Aneuploidy

Cytogenetic and Genome Research, 2011
Apart from a personal tragedy, could Down syndrome, cancer and infertility possibly have something in common? Are there links between a syndrome with physical and mental problems, a tumor growing out of control and the incapability to reproduce?
J.L. Barbero
core   +3 more sources

Analyzing sister chromatid cohesion in mammalian cells

, 2014
The metaphase chromosome spread technique and subsequent analysis of sister chromatid cohesion is used for (clinical) diagnosis of genetic abnormalities that can cause aberrant sister chromatid cohesion.
Parish, Joanna L.; id_orcid, McFarlane-Majeed, Laura, Katherine M. Feeney, Laura McFarlane-Majeed, Feeney, Katherine M., Joanna L. Parish   +5 more
core   +3 more sources

PHB2 Protects Sister-Chromatid Cohesion in Mitosis [PDF]

Current Biology, 2007
SummaryCohesion between sister chromatids is essential for proper chromosome segregation in mitosis. In vertebrate mitotic cells, most cohesin is removed from the chromosome arms [1–4], but centromeric cohesin is protected by shugoshin until the onset of
Akihiro Morimoto, Hideaki Takata, Masatoshi Nakagawa, Morimoto, Akihiro, Kiichi Fukui, Azuma, Takachika, Ono-Maniwa, Rika, Rika Ono-Maniwa, Takata, Hideaki, Kurihara, Daisuke, Susumu Uchiyama, Matsunaga, Sachihiro, Fukui, Kiichi, Takachika Azuma, Ma, Nan, Daisuke Kurihara, Nan Ma, Nakagawa, Masatoshi, Uchiyama, Susumu, Sachihiro Matsunaga   +19 more
core   +4 more sources

Functional Coupling between DNA Replication and Sister Chromatid Cohesion Establishment [PDF]

International Journal of Molecular Sciences, 2021
Ana Boavida, Mohammad Mahtab, Diana Santos   +2 more
exaly   +2 more sources