Results 21 to 30 of about 659,276 (230)

Environmentally friendly protocol for the determination of sitagliptin phosphate in pharmaceutical preparations and biological fluids using l‐tyrosine as a fluorescence probe [PDF]

open access: bronzeLuminescence (Chichester, England Print), 2023
A responsive spectrofluorimetric method was developed for the determination of sitagliptin phosphate using L-tyrosine as a fluorescence probe. The fluorescence intensity of L-tyrosine was quenched with sitagliptin phosphate.
Muhammad Naeem Khan   +2 more
openalex   +2 more sources

Understanding the Adsorption and Desorption of Sitagliptin Phosphate Monohydrate on SS2343, Glass, and PTFE Using QCM-D and Raman Spectroscopy

open access: greenLangmuir, 2022
Cross-contamination during pharmaceutical drug manufacturing can result in expensive recalls. To counter that, companies spend significant time and resources to ensure equipment cleanliness, often relying on the compound solubility data in various ...
Hui Ling Chan   +5 more
openalex   +3 more sources

NiO/CuO@Graphene oxide-modified electrode for sensitive detection of an antidiabetic drug [PDF]

open access: yesScientific Reports
A new, simple, and cost-effective electrochemical sensor was developed for the determination of Sitagliptin phosphate monohydrate (SP) in powder, pharmaceutical tablet form and biological fluids as spiked plasma.
Essam N. Labeeb   +3 more
doaj   +2 more sources

Spectrophotometric Techniques for the Determination of Sitagliptin Phosphate Drugs in Bulk and few Pharmaceutical Products by using MBTH and Ferric Chloride

open access: bronzeInternational Journal of Drug Delivery Technology, 2023
The current study aimed to evolve a method for the detection of sitagliptin (STG) concentration. The method was built on the estimation of absorbance STG wave 612 nm concentration range was (1–18 ppm) and was reacted for oxidative coupling of pregabalin ...
Dalil M H Alher   +2 more
openalex   +2 more sources

Review of sitagliptin phosphate: a novel treatment for type 2 diabetes [PDF]

open access: yesVascular Health and Risk Management, 2007
Baptist GallwitzDept. Medicine IV, Eberhard Karls University, Tuebingen, GermanyAbstract: Sitagliptin (Januvia®, Merck Pharmaceuticals) is a dipeptidyl-peptidase inhibitor (DPP-4 inhibitor) that has recently been approved for the therapy of type 2 ...
Baptist Gallwitz
doaj   +3 more sources

DEVELOPMENT AND VALIDATION OF HPTLC METHOD FOR SIMULTANEOUS ESTIMATION OF DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE, SITAGLIPTIN PHOSPHATE MONOHYDRATE AND METFORMIN HYDROCHLORIDE USING DOE APPROACH

open access: diamondRASAYAN Journal of Chemistry
For simultaneous estimation of DAPA, SITA, and MET in combination, using experiment design, the HPTLC technique was created and validated. The optimized HPTLC technique utilized a mobile phase comprising EA: Methanol: ammonia: GAA in then the ratio of 6 ...
A. B. Patel, P. H. Patel
openalex   +2 more sources

Green and sustainable LC-APCI-MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin [PDF]

open access: yesBMC Chemistry
The International Agency for Research on Cancer categorized nitrosamines as potential or probable human carcinogens. Hence, nitrosamine impurities should be controlled to minimize the cancer risk.
Sriram Pepakayala   +3 more
doaj   +2 more sources

Development and Validation of Stability Indicating RP-HPLC and UV Method for Simultaneous Quantitation of Repaglinide and Sitagliptin Phosphate in Combination

open access: diamond, 2020
The present work describes Stability indicating RP-HPLC and Simultaneous equation UV spectrophotometric method for the quantitative determination of Repaglinide and Sitagliptin phosphate.
Nusrat K. Shaikh   +2 more
openalex   +2 more sources

Formulation And In-vitro Evaluation Of Bilayer Tablets Of Sitagliptin Phosphate

open access: green, 2021
The aim of this work was to plan mucoadhesive bilayered buccal tablets of Sitagliptin Phosphate. Sitagliptin Phosphate is the phosphate salt type of sitagliptin, an orally accessible, serious, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP4) with hypoglycemic movement.
Mayur aware   +2 more
openalex   +2 more sources

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