Computation of the Likelihood in Biallelic Diffusion Models Using Orthogonal Polynomials
Computation, 2014 In population genetics, parameters describing forces such as mutation, migration and drift are generally inferred from molecular data. Lately, approximate methods based on simulations and summary statistics have been widely applied for such inference ...
Claus Vogl
doaj +1 more source
Effect of Soil Anisotropy on Ground Motion Characteristics
Buildings, 2023 Soil transverse isotropy results in different stiffness characteristics in horizontal and vertical directions. However, the effect is usually neglected in seismic motion analysis. In this study, an equivalent linear anisotropic soil model was established
Yuhong Xie, Zhou Cao, Jian Yu
doaj +1 more source
Fast and accurate site frequency spectrum estimation from low coverage sequence data. [PDF]
Bioinformatics, 2015 MOTIVATION: The distribution of allele frequencies across polymorphic sites, also known as the site frequency spectrum (SFS), is of primary interest in population genetics.
Han E, Sinsheimer JS, Novembre J.
europepmc +3 more sources
Inference of Historical Population-Size Changes with Allele-Frequency Data
G3: Genes, Genomes, Genetics, 2020 With up to millions of nearly neutral polymorphisms now being routinely sampled in population-genomic surveys, it is possible to estimate the site-frequency spectrum of such sites with high precision.
Michael Lynch +3 more
doaj +1 more source
IEEE Photonics Journal, 2022 We proposed an all-optical Ka-band microwave long-distance dissemination system based on an optoelectronic oscillator (OEO). In this system, a single tone with high spectrum purity and low phase noise is excited by an injection-locked OEO, and ...
Kaiyu Zhang +3 more
doaj +1 more source
Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories
G3: Genes, Genomes, Genetics, 2017 Inference of demographic history from genetic data is a primary goal of population genetics of model and nonmodel organisms. Whole genome-based approaches such as the pairwise/multiple sequentially Markovian coalescent methods use genomic data from one ...
Annabel C. Beichman +2 more
doaj +1 more source
Correction to: Spatial structure alters the site frequency spectrum produced by hitchhiking. [PDF]
Geneticseuropepmc +2 more sources
The Polymorphism Frequency Spectrum of Finitely Many Sites Under Selection [PDF]
Genetics, 2008 Abstract The distribution of genetic polymorphisms in a population contains information about evolutionary processes. The Poisson random field (PRF) model uses the polymorphism frequency spectrum to infer the mutation rate and the strength of directional selection.
Michael M, Desai, Joshua B, Plotkin
openaire +2 more sources
VCF file used to create Site Frequency spectrum Managua-Apoyeque [PDF]
, 2017 Variant Call Format file used to create Site Frequency spectrum for Managua ...
Meyer, Axel +11 more
core +1 more source
A population genetic approach to mapping neurological disorder genes using deep resequencing. [PDF]
PLoS Genetics, 2011 Deep resequencing of functional regions in human genomes is key to identifying potentially causal rare variants for complex disorders. Here, we present the results from a large-sample resequencing (n = 285 patients) study of candidate genes coupled ...
Rachel A Myers +18 more
doaj +1 more source