Results 31 to 40 of about 283,425 (262)
Can the site-frequency spectrum distinguish exponential population growth from multiple-merger coalescents? [PDF]
Genetics, 2015 Eldon B, Birkner M, Blath J, Freund F.
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Microtremor Recording Surveys to Study the Effects of Seasonally Frozen Soil on Site Response
Sensors, 2023 Microtremor recording tests using an accelerometer were carried out in this paper with the aim of characterizing the effects of seasonally frozen soil on the seismic site response, including the two-direction microtremor spectrum, site predominant ...
Shengyang Chen, Jie Lei, Ya Li
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Viruses, 2022 Due to the emergence of new variants of the SARS-CoV-2 coronavirus, the question of how the viral genomes evolved, leading to the formation of highly infectious strains, becomes particularly important. Three major emergent strains, Alpha, Beta and Delta,
Monika Klara Kurpas +3 more
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Signatures of neutral evolution in exponentially growing tumors: A theoretical perspective.
PLoS Computational Biology, 2021 Recent work of Sottoriva, Graham, and collaborators have led to the controversial claim that exponentially growing tumors have a site frequency spectrum that follows the 1/f law consistent with neutral evolution. This conclusion has been criticized based
Hwai-Ray Tung, Rick Durrett
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Site-frequency-based modeling of the population divergences in Metrosideros polymorpha on the island of Hawaii. [PDF]
, 2022 (A) Schematic representation of simulated demographic models. Time points of divergence between three genetic clusters (T1 and T2), a time point when migration rates changed (TC), effective population sizes for present (N0, N1, and N2) and ancestral (NA ...
Mana Mukai (6093689) +6 more
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Directional Selection and the Site-Frequency Spectrum [PDF]
Genetics, 2001 Abstract In this article we explore statistical properties of the maximum-likelihood estimates (MLEs) of the selection and mutation parameters in a Poisson random field population genetics model of directional selection at DNA sites. We derive the asymptotic variances and covariance of the MLEs and explore the power of the likelihood ...
C D, Bustamante +3 more
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The neutral frequency spectrum of linked sites [PDF]
Theoretical Population Biology, 2017 Abstract We introduce the conditional Site Frequency Spectrum (SFS) for a genomic region linked to a focal mutation of known frequency. An exact expression for its expected value is provided for the neutral model without recombination. Its relation with the expected SFS for two sites, 2-SFS, is discussed.
Ferretti, Luca +5 more
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Site Frequency Spectrum of the Bolthausen-Sznitman Coalescent [PDF]
Latin American Journal of Probability and Mathematical Statistics, 2019 Abstract We derive explicit formulas for the two first moments of he site frequency spectrum ( SFS n,b ) 1≤ b ≤ n
Götz Kersting +2 more
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Expectation of the Site Frequency Spectrum
, 2021 The site frequency spectrum describes variation among a set of n DNA sequences. Its i'th entry (i=1,2,...,n-1) is the number of nucleotide sites at which the mutant allele is present in i copies. Under selective neutrality, random mating, and constant population size, the expected value of the spectrum is well known but somewhat puzzling.
Rogers, Alan R., Wooding, Stephen P.
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