Results 41 to 50 of about 3,871 (235)
Effect of Soil Anisotropy on Ground Motion Characteristics
Buildings, 2023 Soil transverse isotropy results in different stiffness characteristics in horizontal and vertical directions. However, the effect is usually neglected in seismic motion analysis. In this study, an equivalent linear anisotropic soil model was established
Yuhong Xie, Zhou Cao, Jian Yu
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Inference of Historical Population-Size Changes with Allele-Frequency Data
G3: Genes, Genomes, Genetics, 2020 With up to millions of nearly neutral polymorphisms now being routinely sampled in population-genomic surveys, it is possible to estimate the site-frequency spectrum of such sites with high precision.
Michael Lynch +3 more
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IEEE Photonics Journal, 2022 We proposed an all-optical Ka-band microwave long-distance dissemination system based on an optoelectronic oscillator (OEO). In this system, a single tone with high spectrum purity and low phase noise is excited by an injection-locked OEO, and ...
Kaiyu Zhang +3 more
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Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories
G3: Genes, Genomes, Genetics, 2017 Inference of demographic history from genetic data is a primary goal of population genetics of model and nonmodel organisms. Whole genome-based approaches such as the pairwise/multiple sequentially Markovian coalescent methods use genomic data from one ...
Annabel C. Beichman +2 more
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The Polymorphism Frequency Spectrum of Finitely Many Sites Under Selection [PDF]
Genetics, 2008 Abstract The distribution of genetic polymorphisms in a population contains information about evolutionary processes. The Poisson random field (PRF) model uses the polymorphism frequency spectrum to infer the mutation rate and the strength of directional selection.
Michael M, Desai, Joshua B, Plotkin
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A population genetic approach to mapping neurological disorder genes using deep resequencing. [PDF]
PLoS Genetics, 2011 Deep resequencing of functional regions in human genomes is key to identifying potentially causal rare variants for complex disorders. Here, we present the results from a large-sample resequencing (n = 285 patients) study of candidate genes coupled ...
Rachel A Myers +18 more
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Decomposing the site frequency spectrum: the impact of tree topology on neutrality tests [PDF]
Genetics, 2016 Abstract We investigate the dependence of the site frequency spectrum (SFS) on the topological structure of genealogical trees. We show that basic population genetic statistics – for instance estimators of θ or neutrality tests such as Tajima’s D –
Ferretti, Luca +4 more
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The Impact of Sampling Schemes on the Site Frequency Spectrum in Nonequilibrium Subdivided Populations [PDF]
Genetics, 2009 Abstract Using coalescent simulations, we study the impact of three different sampling schemes on patterns of neutral diversity in structured populations. Specifically, we are interested in two summary statistics based on the site frequency spectrum as a function of migration rate, demographic history of the entire substructured ...
Städler, Thomas +4 more
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The hitchhiking effect on the site frequency spectrum of DNA polymorphisms. [PDF]
Genetics, 1995 Abstract The level of DNA sequence variation is reduced in regions of the Drosophila melanogaster genome where the rate of crossing over per physical distance is also reduced. This observation has been interpreted as support for the simple model of genetic hitchhiking, in which directional selection on rare variants, e.g., newly arising ...
J M, Braverman +4 more
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Observed site frequency spectrum data
, 2015 Observed site frequency spectrum data used in FastSimCoal2 ...
Massatti, Rob +9 more
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