Results 41 to 50 of about 45,057 (220)

Investigation of \u3cem\u3ede novo\u3c/em\u3e cholesterol synthetic capacity in the gonads of goldfish (\u3cem\u3eCarassius auratus\u3c/em\u3e) exposed to the phytosterol beta-sitosterol [PDF]

, 2006
Total and intra-mitochondrial gonadal cholesterol concentrations are decreased in fish exposed to the phytoestrogen beta-sitosterol (beta-sit). The present study examined the potential for beta-sit to disrupt de novo cholesterol synthesis in the gonads ...
Drolet, Melissa, MacLatchy, Deborah L., Sharpe, Rainie L.   +2 more
core   +1 more source

Endosperm sterol phenotype and germination in wheat [PDF]

, 1976
Free and conjugated sterols of endosperm, coats, scutellum, coleoptile and roots have been analysed at different germination stages in two wheat cultivars with different endosperm sterol phenotypes.
Carbonero Zalduegui, Pilar, García Olmedo, Francisco, Torres, V.   +2 more
core   +2 more sources

Cationic mRNA Lipid Nanoparticles for Ex Vivo NanoCAR‐T Cell Engineering

Advanced Science, EarlyView.
This study compares charge‑neutral and cationic lipidnanoparticles (LNPs) for ex vivo mRNA delivery to T cells, revealing distinctdependencies on medium composition and T cell activation. Where conventional LNPs benefit from ApoE‐dependent T cell targeting, cationic DOTAP‑modified LNPs mediate unspecific charge‑dependent transfection.
Laure Harinck, Stijn De Munter, Margo De Velder, Joline Ingels, Dominika Berdecka, Ine Lentacker, Winnok H. De Vos, Bart Vandekerckhove, Kevin Braeckmans, Koen Raemdonck   +9 more
wiley   +1 more source

Phytosterol ester processing in the small intestine: impact on cholesterol availability for absorption and chylomicron cholesterol incorporation in healthy humans[S]

Journal of Lipid Research, 2011
Phytosterols (plant sterols and stanols) can lower intestinal cholesterol absorption, but the complex dynamics of the lipid digestion process in the presence of phytosterol esters (PEs) are not fully understood.
Marie Josèphe Amiot, Diny Knol, Nicolas Cardinault, Marion Nowicki, Romain Bott, Claudine Antona, Patrick Borel, Jean-Paul Bernard, Guus Duchateau, Denis Lairon   +9 more
doaj   +1 more source

The Plasma Distribution of Non-cholesterol Sterol Precursors and Products of Cholesterol Synthesis and Phytosterols Depend on HDL Concentration

Frontiers in Nutrition, 2022
Non-cholesterol sterols are transported in plasma lipoproteins and are consequently important in cholesterol metabolism. We investigated the distribution of non-cholesterol sterol precursors of cholesterol synthesis (NCSPCS), oxysterols, and phytosterols
Valéria Sutti Nunes, Eliton Juniro da Silva, Guilherme da Silva Ferreira, Sayonara Ivana Santos de Assis, Patrícia Miralda Cazita, Edna Regina Nakandakare, Vanessa Helena de Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintão   +8 more
doaj   +1 more source

Aloe vera–Based Green Synthesis of Silver Nanoparticles With Characterization, Potent Antibacterial and Antioxidant Properties

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Green synthesis has emerged as a suitable alternative to the traditional method for manufacturing nanoparticles (NPs) as it provides a safer, sustainable, healthy, and environmental path for the NPs synthesis. Silver nanoparticles (AgNPs) were prepared using a green method with locally sourced Aloe vera leaf extract.
Janaki Baral, Sushant Timalsina, Sujan Dhungana, Laxmi Tiwari, Devendra Khadka, Bhoj Raj Poudel   +5 more
wiley   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]

, 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi, Christiansen, Blaine, Emami, Shahin, Goudarzi, Ramin   +3 more
core   +1 more source

Evaluation of Agave angustifolia as a Sustainable Alternative to Synthetic Pesticides: Phytochemical Composition and Multi‐Trophic Bioactivity

Flavour and Fragrance Journal, EarlyView.
The pesticidal potential of Agave angustifolia by assessing its anti‐nematic, antimicrobial, and insecticidal activities, alongside phytochemical profiling. ABSTRACT Plant diseases caused by fungi, bacteria, nematodes, and viruses contribute significantly to annual crop losses and economic hardship. Reliance on chemical pesticides, over a thousand used
Rashika Tamta, Shilpi Rawat, Himani Karakoti, Tannu Rani, Pooja Bargali, Ravendra Kumar, Stefania Garzoli, Renu Pandey   +7 more
wiley   +1 more source

Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8

Journal of Lipid Research, 2002
The plasma concentrations of cholesterol precursor sterols and plant sterols vary over a 5- to 10-fold range among normolipidemic individuals, and provide indices of the relative rates of cholesterol synthesis and fractional absorption.
Knut E. Berge, Klaus von Bergmann, Dieter Lutjohann, Rudy Guerra, Scott M. Grundy, Helen H. Hobbs, Jonathan C. Cohen   +6 more
doaj   +1 more source