Results 121 to 130 of about 3,038,180 (280)

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

A fusion protein’s weak link: functional constraints revealed by inhibitory peptide interaction with the parainfluenza fusion protein

mBio
Human parainfluenza viruses (HPIVs) cause significant respiratory illnesses including croup and pneumonia. HPIV infection begins with fusion of viral and host cell membranes, driven by the coordinated actions of the attachment (HN) and fusion (F ...
Maximilian Crosby, Ariel J. Kuhn, Gillian Zipursky, Tara C. Marcink, Kyle Stearns, Elizabeth B. Sobolik, Dariia Vyshenska, Jee Ching Mook, Alexander L. Greninger, Matteo Porotto, Samuel H. Gellman, Anne Moscona   +11 more
doaj   +1 more source

Synthesis of a Three-Helix Bundle Protein by Reductive Amination

, 2016
An organic trialdehyde, TRIPOD (2), was designed as a template for the synthesis of a three-helix bundle protein. Crystallographic data indicate that the aldehyde groups are appropriately spaced to maximize hydrophobic interactions between the chains of ...
Tomikazu Sasaki (389638), Deborah C. Tahmassebi (2244292)   +1 more
core   +1 more source

Coordination Bridges in Confined‐Water Domains Enable Partially Desolvated Zn2+ Transport in Aqueous Zinc‐Ion Batteries

Advanced Materials, EarlyView.
A multifunctional polymer layer with amide and imidazolium groups simultaneously suppresses dendrite growth and hydrogen evolution in Zn‐ion batteries. By providing Zn2+ binding sites and forming a confined‐water domain that acts as a coordination bridge, it boosts single‐ion conductivity and stability, enabling 4000 stable cycles in Zn‐I2 full cells ...
Jin Seong Cha, Dongmin Jeon, Kyungmi Kim, Yuna Hwang, Eun Jeong Yoon, Donghee Gueon, Young‐Woo Choi, Chan‐Woo Lee, Jung Hoon Yang   +8 more
wiley   +1 more source

Helix-bundle and C-terminal GPCR domains differentially influence GRK-specific functions and β-arrestin-mediated regulation [PDF]

G protein-coupled receptors (GPCRs) orchestrate diverse physiological responses via signaling through G proteins, GPCR kinases (GRKs), and arrestins.
Ziegler, Carla, Haider, Raphael S., Schulz, Stefan, Klement, Laura, Drube, Julia, Matthees, Edda S. F., Blum, Nina K., Weitzel, Verena, Hoffmann, Carsten, Trüpschuch, Thimea, Reichel, Mona   +10 more
core   +1 more source

Blending With Insulating Polymers Enables Stable Anti‐Ambipolar Characteristics in n‐Type Organic Mixed‐Conductors for Heterogeneous Spiking Neurons

Advanced Materials, EarlyView.
A polymer blend of n‐type OMIEC P(gNDI‐gT2) with insulating PMMA yields mechanically stabilized, anti‐ambipolar organic electrochemical transistors (OECTs) with tunable ionic‐electronic transport. This blending allows low‐power, fast‐spiking heterogeneous Hodgkin–Huxley neurons, enabling biomimetic frequency deconvolution and reservoir computing, which
Zachary Laswick, Ariel Lifer, Catherine Beaumont, Liad Hayoun, Priscila Cavassin, Zeinab Hamid, Dilara Meli, William Dupont, Lincoln J. Lauhon, Iain McCulloch, Gitti L. Frey, Giovanni Maria Matrone, Jonathan Rivnay   +12 more
wiley   +1 more source

Research strategies of the N-peptide fusion inhibitor: a promising direction for discovering novel antivirals

Journal of Virology
AIDS, caused by HIV-1, is a devastating condition that severely compromises the human immune system, often resulting in fatal consequences. The primary therapeutic approach for AIDS involves a combination of multiple agents, known as “cocktail therapy ...
Yan Huang, Guodong Liang, Taoran Wang, Yuheng Ma, Lu Ga, Lijun Sun, Xiao Qi, Wei Zhang, Ruijuan Li, Yan Zhao, Zhao Meng, Xin Gao   +11 more
doaj   +1 more source

Structural Studies of Amphiphilic 4-Helix Bundle Peptides Incorporating Designed Extended Chromophores for Nonlinear Optical Biomolecular Materials

, 2016
Extended conjugated chromophores containing (porphinato)zinc components that exhibit large optical polarizabilities and hyperpolarizabiliites are incorporated into amphiphilic 4-helix bundle peptides via specific axial histidyl ligation of the metal. The
Sophia P. Wu (2520853), Thomas Gog (2520856), Ivan Miloradovic (2520850), Michael J. Therien (1371579), J. Kent Blasie (1317141), Joseph Strzalka (1477027), Ivan Kuzmenko (1268562), Ting Xu (215531), Andrey Tronin (1910755)   +8 more
core   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source

An α/β-Peptide Helix Bundle with a Pure β³-Amino Acid Core and a Distinctive Quaternary Structure

, 2016
An α/β-Peptide Helix Bundle with a Pure β3-Amino Acid Core and a Distinctive Quaternary ...
Michael W. Giuliano (2360419), Samuel H. Gellman (621247), W. Seth Horne (1331739)   +2 more
core   +1 more source