Results 111 to 120 of about 3,038,180 (280)

Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. [PDF]

, 2011
Transmembrane α-helices play a key role in many receptors, transmitting a signal from one side to the other of the lipid bilayer membrane. Bacterial chemoreceptors are one of the best studied such systems, with a wealth of biophysical and mutational data
Judith P Armitage, Judith P. Armitage, Sansom, MS, Armitage Judith P., Mark S P Sansom, Armitage, JP, Benjamin A Hall, Sansom Mark S. P., Hall, BA, Benjamin A. Hall, Mark S. P. Sansom, Hall Benjamin A.   +11 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Clustomesogen Showing Sub‐Zero Liquid Crystal Properties: Supramolecular Assembly Between Cs2[Mo6Ii8(OCOC2F5)6] and Hexaethylenoxide Containing Mesogenic Dimers

Advanced Materials, EarlyView.
Associating a red‐NIR phosphorescent octahedral hexanuclear molybdenum cluster compound with hexaethyleneoxide chains bearing mesogenic units on both ends leads to an emissive hybrid liquid crystal showing mesomorphism on a very unusual temperature range down to −25°C.
Killiann Heinz, Jeanne Rebours, Zoulikha Zerrouqi, Noée Dumait, Maria Amela‐Cortes, Nikolai Scheuring, Sara Simonovska, Sebastian Marino, Max Ebert, Stéphane Cordier, Sabine Laschat, Yann Molard   +11 more
wiley   +1 more source

Polyclonal and monoclonal antibodies specific for the six-helix bundle of the human respiratory syncytial virus fusion glycoprotein as probes of the protein post-fusion conformation

Virology, 2014
Human respiratory syncytial virus (hRSV) has two major surface glycoproteins (G and F) anchored in the lipid envelope. Membrane fusion promoted by hRSV_F occurs via refolding from a pre-fusion form to a highly stable post-fusion state involving large conformational changes of the F trimer.
Palomo, Concepción, Mas, Vicente, Vázquez, Mónica, Cano, Olga, Luque, Daniel, Terrón, María C., Calder, Lesley J., Melero, José A.   +7 more
openaire   +2 more sources

Packing and recognition of protein structural elements: a new approach applied to the 4-helix bundle of myohemerythrin.

, 1993
International audienceWe present a novel search strategy for determining the optimal packing of protein secondary structure elements. The approach is based on conformational energy optimization using a predetermined set of side chain rotamers and ...
Lavery, R., Tuffery, P.
core   +2 more sources

Mini-bacterioferritins: structural insight into a ferritin-like protein from the anaerobic methane-oxidising archaeon Candidatus Methanoperedens carboxydivorans

Communications Biology
Ferritins are ubiquitous among life forms, as they are essential for iron homeostasis. Here, we unveiled a novel member of the ferritin family, baptised mini-bacterioferritin.
Martijn Wissink, Sylvain Engilberge, Pedro Leão, Robert S. Jansen, Mike S. M. Jetten, Mélissa Belhamri, Olivier N. Lemaire, Antoine Royant, Cornelia U. Welte, Tristan Wagner   +9 more
doaj   +1 more source

Elucidating the Molecular Mechanism of 3D1 Antibody Binding to a Swine Enteric Coronavirus Antigen

Viruses
The broadly neutralizing monoclonal antibody 3D1 potently neutralizes SADS-CoV by targeting a conserved epitope within the heptad repeat 1 (HR1) domain of the viral spike protein.
Liangminghui Zhang, Ze Liang, Guang Yang, Lei Yan   +3 more
doaj   +1 more source

Fiber‐Format Flexible Linear Electrostatic Motors

Advanced Materials, EarlyView.
A flexible coaxial fibre‐format electrostatic motor enables backdrivable and reversible linear actuation with high force density and functionality under bending, offering a scalable actuation platform for soft and wearable robotics. ABSTRACT Linear motion is fundamental to robotics, yet existing solutions are either rigid electromagnetic motors or ...
Sylvain Schaller, Herbert Shea
wiley   +1 more source

The de novo design and stabilization of self-assembling helix bundle proteins and the dissociative inhibition of HIV-1 protease

, 1995
A series of peptides capable of self-assembling into helix bundle proteins was designed, synthesized, and studied. The peptide Leu4 was shown to exist primarily as a parallel two-helix bundle in aqueous solution. The peptide Leu6 was shown to form a four-
Lutgring, Ray Anthony
core   +1 more source

Identification of Residues in Lassa Virus Glycoprotein Subunit 2 That Are Critical for Protein Function

Pathogens, 2018
Lassa virus (LASV) is an Old World arenavirus, endemic to West Africa, capable of causing hemorrhagic fever. Currently, there are no approved vaccines or effective antivirals for LASV.
Katherine A. Willard, Jacob T. Alston, Marissa Acciani, Melinda A. Brindley   +3 more
doaj   +1 more source