Results 101 to 110 of about 3,038,180 (280)

Structural mechanism of trimeric HIV-1 envelope glycoprotein activation.

PLoS Pathogens, 2012
HIV-1 infection begins with the binding of trimeric viral envelope glycoproteins (Env) to CD4 and a co-receptor on target T-cells. Understanding how these ligands influence the structure of Env is of fundamental interest for HIV vaccine development ...
Erin E H Tran, Mario J Borgnia, Oleg Kuybeda, David M Schauder, Alberto Bartesaghi, Gabriel A Frank, Guillermo Sapiro, Jacqueline L S Milne, Sriram Subramaniam   +8 more
doaj   +1 more source

Three-Helix Bundle DNA Tiles Self-Assemble into 2D Lattice or 1D Templates for Silver Nanowires

, 2016
We present a DNA nanostructure, the three-helix bundle (3HB), which consists of three double helical DNA domains connected by six immobile crossover junctions such that the helix axes are not coplanar.
Hao Yan (134033), Gleb Finkelstein (423586), Sung Ha Park (1577881), Robert Barish (2686543), Hanying Li (1591387), John H. Reif (2219965), Thomas H. LaBean (1650577)   +6 more
core   +1 more source

Tracking Battery Microstructural Degradation Through Directional Thermal Transport Signatures

Advanced Functional Materials, EarlyView.
In lithium‐ion batteries, heat conduction varies between the through‐plane and in‐plane directions because of the cell's layered structure. Therefore, cell degradation influences thermal conductivity in each direction uniquely due to detailed microstructural and compositional changes.
Mohammad Shoghi Tekmedash, Rituparna Mohanty, Jack Leber, David Nageb, Mirella Richard, Sharan Singh, Amin Reihani   +6 more
wiley   +1 more source

Design and Characterization of a Zn²⁺-Binding Four-Helix Bundle Protein in the Biophysical Chemistry Laboratory

, 2015
A biophysical chemistry laboratory project is described that combines classroom and laboratory experiences to design and characterize a Zn2+-binding four-helix bundle protein.
Zohar Nawlo (1311117), Kylie F. Sikorski (1311129), Paola J. Burburan (1311114), Ana Galesic (1311123), Brian J. Stockman (1311120), Jill S. Asheld (1311126)   +5 more
core   +1 more source

Optimizing NiMo Electrocatalyst Coatings for Hydrogen Evolution in Alkaline Electrolysis With The Machine Learning‐Guided Autonomous Platform CatBot

Advanced Functional Materials, EarlyView.
This work presents a closed‐loop optimization workflow integrating CatBot, an automated synthesis and testing system, to discover NiMo hydrogen‐evolution catalysts. CatBot synthesised and evaluated 228 unique samples, identifying the best performing catalysts for transfer to nickel‐foam electrodes. The best candidate is highly active, reaching 1 Acm−2${
Paolo Vincenzo Freiesleben de Blasio, Jonas Elsborg, Elif Coşkun, Andreas Burger, Pradipkumar Manubhai Leuaa, Thu Pham Anh Phan, Jin Hyun Chang, Christodoulos Chatzichristodoulou   +7 more
wiley   +1 more source

Basic Tilted Helix Bundle – A new protein fold in human FKBP25/FKBP3 and HectD1

, 2014
In this paper, we describe the structure of a N-terminal domain motif in nuclear-localized FKBP251–73, a member of the FKBP family, together with the structure of a sequence-related subdomain of the E3 ubiquitin ligase HectD1 that we show belongs to the ...
Almlöf, Jonas,, Arrowsmith , C., Yee, Adelinda,, Li, Yanjun,, Lemak, Alexander,, Farès, Christophe,, Dhe-Paganon, Sirano,, Li, Y., Dhe-Paganon, S., Almlöf , J., Montecchio, Meri,, Lemak, A., Helander, Sara,, Montecchio , M., Sunnerhagen, M., Sunnerhagen, Maria,, Arrowsmith, Cheryl H,, Helander, S., Farès, C., Yee, A.   +19 more
core   +1 more source

Fiber‐Based Wearable Electronics as Adaptive Biointerfaces for Healthcare Applications

Advanced Functional Materials, EarlyView.
Fiber‐based wearable electronics have been extensively studied as adaptive healthcare biointerfaces. In this review, we classify and introduce fiber‐based systems according to biointerface design, conductive materials, transduction mechanisms, and healthcare applications, and provide a perspective on their translation toward reliable, continuous ...
Sangwoo Hong, Jinsol Kim, Yoonjae Jeong, Sejong Kang, Daeho Lee, Seung Hwan Ko   +5 more
wiley   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Atomic structures of a bacteriocin targeting Gram-positive bacteria

Nature Communications
Due to envelope differences between Gram-positive and Gram-negative bacteria, engineering precision bactericidal contractile nanomachines requires atomic-level understanding of their structures; however, only those killing Gram-negative bacteria are ...
Xiaoying Cai, Yao He, Iris Yu, Anthony Imani, Dean Scholl, Jeff F. Miller, Z. Hong Zhou   +6 more
doaj   +1 more source

Structure-Guided Design of Peptide Inhibitors Targeting Class I Viral Fusion Proteins

Pathogens
Viral fusion proteins are indispensable mediators of viral entry that orchestrate the fusion of viral and host membranes, making them primary targets for antiviral interventions.
Narendra Kumar Gonepudi, Harry Baffour Awuah, Wang Xu, Revansiddha H. Katte, Maolin Lu   +4 more
doaj   +1 more source