Results 11 to 20 of about 529,334 (314)

Redox proteomic analysis of the gastrocnemius muscle from adult and old mice

open access: yesData in Brief, 2015
The data provides information in support of the research article, “Differential Cysteine Labeling and Global Label-Free Proteomics Reveals an Altered Metabolic State in Skeletal Muscle Aging”, Journal of Proteome Research, 2014, 13 (11), 2008–21 [1]. Raw
Brian McDonagh   +4 more
doaj   +1 more source

Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism

open access: yesSkeletal Muscle, 2020
Background Distal arthrogryposis (DA) is a group of autosomal dominant skeletal muscle diseases characterized by congenital contractures of distal limb joints.
Yiming Guo   +8 more
doaj   +1 more source

Skeletal Muscle Channelopathies [PDF]

open access: yesNeurotherapeutics, 2018
Skeletal muscle channelopathies are rare heterogeneous diseases with marked genotypic and phenotypic variability. These disorders cause lifetime disability and impact quality of life. Despite advances in understanding of the molecular pathology of these disorders, the diverse phenotypic manifestations remain a challenge in diagnosis, therapeutic ...
Lauren, Phillips, Jaya R, Trivedi
openaire   +2 more sources

Skeletal Muscle Mitochondria and Aging: A Review

open access: yesJournal of Aging Research, 2012
Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines in skeletal muscle mitochondria are thought to play a primary role in this process.
Courtney M. Peterson   +2 more
doaj   +1 more source

Skeletal Muscle Physiology

open access: yesThe Scientific World Journal, 2013
In the beginning of the last century, muscle proteins were viewed as static structural molecules not capable of being utilized by other tissues or organs. This concept was accepted until the 30s, where Rudolf Schoenheimer presented strong evidences about the “Dynamic State of Body Constituents,” which means that skeletal muscle is not only capable of ...
Lucas Guimarães-Ferreira   +3 more
openaire   +3 more sources

Targeting healthspan to optimally combat non-communicable disease in an aging world

open access: yesSports Medicine and Health Science, 2019
Human lifespan and life expectancy have increased worldwide, but the number of years that we spend free of chronic or debilitating disorders, known as healthspan, has not shifted along with increased lifespan.
Joshua C. Drake, Zhen Yan
doaj   +1 more source

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells [PDF]

open access: yesJournal of Clinical Investigation, 2010
Skeletal muscle damaged by injury or by degenerative diseases such as muscular dystrophy is able to regenerate new muscle fibers. Regeneration mainly depends upon satellite cells, myogenic progenitors localized between the basal lamina and the muscle fiber membrane.
F. S. Tedesco   +4 more
openaire   +4 more sources

An updated C. elegans nuclear body muscle transcriptome for studies in muscle formation and function

open access: yesSkeletal Muscle, 2023
The body muscle is an important tissue used in organisms for proper viability and locomotion. Although this tissue is generally well studied and characterized, and many pathways have been elucidated throughout the years, we still lack a comprehensive ...
Anna L. Schorr   +3 more
doaj   +1 more source

Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling

open access: yesSkeletal Muscle, 2020
Background In Duchenne muscular dystrophy (DMD), DYSTROPHIN deficiency exposes myofibers to repeated cycles of contraction/degeneration, ultimately leading to muscle loss and replacement by fibrotic tissue.
Luca Caputo   +6 more
doaj   +1 more source

Bioelectrical impedance vectors analysis (BIVA) in older adults according to level of physical activity and muscle strength: a comparison of classic and specific approaches

open access: yesFrontiers in Aging
IndroductionBioelectrical Impedance Analysis (BIA) is a widely used method to assess body composition. Traditional BIA models use predictive equations without considering individual characteristics such as age, sex, and activity level.
Ismael Figueiredo Rabelo   +7 more
doaj   +1 more source

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