Results 11 to 20 of about 2,591,688 (405)

Skeletal Muscle Channelopathies [PDF]

Neurologic Clinics, 2020
Skeletal muscle channelopathies are rare genetic neuromuscular conditions that include the nondystrophic myotonias and periodic paralyses. They cause disabling muscle symptoms and can limit educational potential, work opportunities, socialization, and quality of life. Effective therapy is available, making it essential to recognize and treat this group
Vivekanandam, V, Munot, P, Hanna, M, Matthews, E   +3 more
openaire   +3 more sources

Perspectives on skeletal muscle stem cells

Nature Communications, 2021
Skeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle stem cells (MuSCs). In this review, we introduce recently developed technologies and the mechanistic insights they provide to the understanding of MuSC biology ...
F. Relaix, M. Bencze, M. Borok, A. Der Vartanian, F. Gattazzo, D. Mademtzoglou, S. Pérez-Díaz, A. Prola, P. C. Reyes-Fernandez, A. Rotini, Taglietti   +10 more
semanticscholar   +1 more source

Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging

International Journal of Molecular Sciences, 2021
The maintenance of mitochondrial integrity is critical for muscle health. Mitochondria, indeed, play vital roles in a wide range of cellular processes, including energy supply, Ca2+ homeostasis, retrograde signaling, cell death, and many others.
J. Leduc‐Gaudet, S. Hussain, E. Barreiro, G. Gouspillou   +3 more
semanticscholar   +1 more source

Embedding Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease in the Home and Community Setting: A Rapid Review

Frontiers in Rehabilitation Sciences, 2022
This paper presents a rapid review of the literature for the components, benefits, barriers, and facilitators of pulmonary rehabilitation for chronic obstructive pulmonary disease (COPD) people in-home and community-based settings.
Túlio Medina Dutra de Oliveira, Adriano Luiz Pereira, Giovani Bernardo Costa, Liliane P. de Souza Mendes, Liliane P. de Souza Mendes, Leonardo Barbosa de Almeida, Marcelo Velloso, Carla Malaguti   +7 more
doaj   +1 more source

Extracellular matrix: an important regulator of cell functions and skeletal muscle development

Cell & Bioscience, 2021
Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal ...
Weiya Zhang, Yuan-yuan Liu, Hong Zhang
semanticscholar   +1 more source

Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

Journal of Cachexia, Sarcopenia and Muscle, 2021
Satellite cells (SCs) are critical to skeletal muscle regeneration. Inactivation of SCs is linked to skeletal muscle loss. Transferrin receptor 1 (Tfr1) is associated with muscular dysfunction as muscle‐specific deletion of Tfr1 results in growth ...
Hongrong Ding, Shujie Chen, Xiaohan Pan, Xiaoshuang Dai, Guihua Pan, Ze Li, Xudong Mai, Ye Tian, Susu Zhang, Bingdong Liu, Guangchao Cao, Zhicheng Yao, Xiangping Yao, Liang Gao, Li Yang, Xiaoyan Chen, Jia Sun, Hong Chen, Mulan Han, Yulong Yin, Guohuan Xu, Huijun Li, Weidong Wu, Zheng Chen, Jingchao Lin, Liping Xiang, Jun Hu, Yan Lu, Xiao Zhu, Liwei Xie   +29 more
semanticscholar   +1 more source

Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage [PDF]

, 2020
Glycogenin is considered to be an essential primer for glycogen biosynthesis. Nevertheless, patients with glycogenin-1 deficiency due to biallelic GYG1 (NM_004130.3) mutations can store glycogen in muscle.
Dellgren, Göran, Glamuzina, Emma, Hedberg-Oldfors, Carola, Hernandez-Lain, Aurelio, Kornblum, Cornelia, Oldfors, Anders, Roach, Peter, Sandstedt, Joakim, Tasca, Giorgio, Thomsen, Christer, Visuttijai, Kittichate   +10 more
core   +1 more source

Skeletal muscle ultrasound [PDF]

Neurological Research, 2011
Muscle ultrasound is a convenient technique to visualize normal and pathological muscle tissue as it is non-invasive and real-time. Neuromuscular disorders give rise to structural muscle changes that can be visualized with ultrasound: atrophy can be objectified by measuring muscle thickness, while infiltration of fat and fibrous tissue increases muscle
Pillen, S., Alfen, N. van
openaire   +4 more sources

Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy

Cells, 2020
Insulin-like growth factor-1 (IGF-1) is a key growth factor that regulates both anabolic and catabolic pathways in skeletal muscle. IGF-1 increases skeletal muscle protein synthesis via PI3K/Akt/mTOR and PI3K/Akt/GSK3β pathways. PI3K/Akt can also inhibit
Tadashi Yoshida, P. Delafontaine
semanticscholar   +1 more source

Resistance exercise training improves mucociliary clearance in subjects with COPD: A randomized clinical trial

Pulmonology, 2019
Introduction Elastic tubing was recently investigated as an alternative to the conventional resistance training (RT) in chronic obstructive pulmonary disease (COPD). The effects of RT on the mucociliary system have not yet been reported in the literature.
B.S.A. Silva, D. Ramos, G.N. Bertolini, A.P.C.F. Freire, M.R. Leite, C.A. Camillo, L.A. Gobbo, E.M.C. Ramos   +7 more
doaj   +3 more sources