Results 101 to 110 of about 130,952 (308)

Impaired Skeletal Muscle Regeneration Induced by Macrophage Depletion Could Be Partly Ameliorated by MGF Injection

Frontiers in Physiology, 2019
Skeletal muscle injury is one of the most common injuries in sports medicine. Our previous study found that macrophage depletion impairs muscle regeneration and that mechano growth factor (MGF) may play an important role in this process. However, whether
Xiaoguang Liu, Zhigang Zeng, Zhigang Zeng, Linlin Zhao, Peijie Chen, Weihua Xiao   +5 more
doaj   +1 more source

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo. [PDF]

, 2014
Tissue-engineered skeletal muscle can serve as a physiological model of natural muscle and a potential therapeutic vehicle for rapid repair of severe muscle loss and injury.
Bursac, N, Engelmayr, GC, Fontanella, AN, Juhas, M, Palmer, GM   +4 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

RAGE in the pathophysiology of skeletal muscle

Journal of Cachexia, Sarcopenia and Muscle, 2018
Emerging evidence suggests that the signalling of the Receptor for Advanced Glycation End products (RAGE) is critical for skeletal muscle physiology controlling both the activity of muscle precursors during skeletal muscle development and the correct ...
Francesca Riuzzi, Guglielmo Sorci, Roberta Sagheddu, Sara Chiappalupi, Laura Salvadori, Rosario Donato   +5 more
doaj   +1 more source

BMSC Transplantation Aggravates Inflammation, Oxidative Stress, and Fibrosis and Impairs Skeletal Muscle Regeneration

Frontiers in Physiology, 2019
Skeletal muscle contusion is one of the most common muscle injuries in sports medicine and traumatology. Bone marrow mesenchymal stem cell (BMSC) transplantation has been proposed as a promising strategy to promote skeletal muscle regeneration.
Xiaoguang Liu, Lifang Zheng, Yongzhan Zhou, Yingjie Chen, Peijie Chen, Weihua Xiao   +5 more
doaj   +1 more source

The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]

, 2015
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Anna eNoble, Colin eSharpe, David J. Goldhamer, Erika C. Jorge, Gabrielle eKardon, Julia eMeireles Nogueira, Julia eMeireles Nogueira, Katarzyna eHawrot, Susanne eDietrich, William M. Wood   +9 more
core   +2 more sources

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Generation of both an shRNA-resistant MEF2A over expression construct and a dominant negative construct in adenovirus for rescue and knockout experiments in muscle [PDF]

, 2015
The Myocyte Enhancer Factor-2, or MEF2, transcription factor family is necessary for the differentiation and regeneration of both skeletal and cardiac muscle tissue.
Comeau, Kathryn Marie
core   +1 more source

Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration [PDF]

, 2018
Pathological conditions affecting skeletal muscle function may lead to irreversible volumetric muscle loss (VML). Therapeutic approaches involving acellular matrices represent an emerging and promising strategy to promote regeneration of skeletal ...
A Mauro, A Otto, A Pasut, A Urciuolo, AJ Beattie, AJ Merrell, AR Gillies, AR Gillies, B Blaauw, B Perniconi, BE Uygun, BM Sicari, BM Sicari, BN Brown, C Borselli, C Fuoco, C Lepper, C-H Lin, CF Bentzinger, DC Sullivan, EC Moran, EK Merritt, F Gattazzo, G Totonelli, H Collins-Hooper, HC Ott, J Dziki, J Zhang, JE Valentin, JM Fishman, JM Fishman, K Garg, M Caralt, M Juhas, M Piccoli, M Quarta, M Quarta, MJ Elliott, MM Murphy, MT Conconi, MT Wolf, NA Dumont, P Coppi De, P Macchiarini, PB Patil, Q Qing, R Langer, R Sambasivan, S-H Mirmalek-Sani, S-K Goh, SJ Mathew, SM Greising, TH Petersen, TJ Keane   +53 more
core   +4 more sources