Results 1 to 10 of about 22,342 (258)

Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels.

open access: yesPLoS ONE, 2012
Skeletal muscle atrophy can occur as a consequence of immobilization and/or starvation in the majority of vertebrates studied. In contrast, hibernating mammals are protected against the loss of muscle mass despite long periods of inactivity and lack of ...
Eva Andres-Mateos   +13 more
doaj   +1 more source

Skeletal muscle in health and disease

open access: yesDisease Models & Mechanisms, 2020
Skeletal muscle fibres are multinucleated cells that contain postmitotic nuclei (i.e. they are no longer able to divide) and perform muscle contraction.
Jennifer Morgan, Terence Partridge
doaj   +1 more source

Transplantation to study satellite cell heterogeneity in skeletal muscle

open access: yesFrontiers in Cell and Developmental Biology, 2022
Skeletal muscle has a remarkable capacity to regenerate throughout life, which is mediated by its resident muscle stem cells, also called satellite cells. Satellite cells, located periphery to the muscle fibers and underneath the basal lamina, are an indispensable cellular source for muscle regeneration. Satellite cell transplantation into regenerating
Bahareh Hekmatnejad   +3 more
openaire   +3 more sources

Regeneration competent satellite cell niches in rat engineered skeletal muscle

open access: yesFASEB BioAdvances, 2019
Satellite cells reside in defined niches and are activated upon skeletal muscle injury to facilitate regeneration. Mechanistic studies of skeletal muscle regeneration are hampered by the inability to faithfully simulate satellite cell biology in vitro ...
Malte Tiburcy   +7 more
doaj   +1 more source

Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle

open access: yesFrontiers in Physiology, 2014
Adult skeletal muscle possesses a remarkable regenerative ability that is dependent on satellite cells. However, skeletal muscle is replaced by fatty and fibrous connective tissue in several pathological conditions.
Akiyoshi eUezumi   +2 more
doaj   +1 more source

Pax7 and myogenic progression in skeletal muscle satellite cells [PDF]

open access: yesJournal of Cell Science, 2006
Skeletal muscle growth and regeneration are attributed to satellite cells - muscle stem cells resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells express the transcription factor Pax7 and when activated, coexpress Pax7 with MyoD. Most then proliferate, downregulate Pax7 and differentiate.
Zammit, Peter   +6 more
openaire   +4 more sources

Protein Availability and Satellite Cell Dynamics in Skeletal Muscle

open access: yesSports Medicine, 2018
Human skeletal muscle satellite cells are activated in response to both resistance and endurance exercise. It was initially proposed that satellite cell proliferation and differentiation were only required to support resistance exercise-induced hypertrophy.
Baubak Shamim   +2 more
openaire   +4 more sources

Skeletal muscle satellite cells cultured in simulated microgravity [PDF]

open access: yesIn Vitro Cellular & Developmental Biology - Animal, 1997
Satellite cells are postnatal myoblasts responsible for providing additional nuclei to growing or regenerating muscle cells. Satellite cells retain the capacity to proliferate and differentiate in vitro and, therefore, provide a useful model to study postnatal muscle development.
G, Molnar   +3 more
openaire   +2 more sources

Long Noncoding Ribonucleic Acid MSTRG.59589 Promotes Porcine Skeletal Muscle Satellite Cells Differentiation by Enhancing the Function of PALLD

open access: yesFrontiers in Genetics, 2019
Skeletal muscle satellite cells are a class of undifferentiated mononuclear myogenic stem cells distributed between the myofibroblast and membrane basement.
Long Li   +6 more
doaj   +1 more source

Satellite cells from dystrophic muscle retain regenerative capacity

open access: yesStem Cell Research, 2015
Duchenne muscular dystrophy is an inherited disorder that is characterized by progressive skeletal muscle weakness and wasting, with a failure of muscle maintenance/repair mediated by satellite cells (muscle stem cells).
Luisa Boldrin   +2 more
doaj   +1 more source

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