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Skeletal muscle atrophy can occur as a consequence of immobilization and/or starvation in the majority of vertebrates studied. In contrast, hibernating mammals are protected against the loss of muscle mass despite long periods of inactivity and lack of ...
Eva Andres-Mateos +13 more
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Skeletal muscle in health and disease
Skeletal muscle fibres are multinucleated cells that contain postmitotic nuclei (i.e. they are no longer able to divide) and perform muscle contraction.
Jennifer Morgan, Terence Partridge
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Transplantation to study satellite cell heterogeneity in skeletal muscle
Skeletal muscle has a remarkable capacity to regenerate throughout life, which is mediated by its resident muscle stem cells, also called satellite cells. Satellite cells, located periphery to the muscle fibers and underneath the basal lamina, are an indispensable cellular source for muscle regeneration. Satellite cell transplantation into regenerating
Bahareh Hekmatnejad +3 more
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Regeneration competent satellite cell niches in rat engineered skeletal muscle
Satellite cells reside in defined niches and are activated upon skeletal muscle injury to facilitate regeneration. Mechanistic studies of skeletal muscle regeneration are hampered by the inability to faithfully simulate satellite cell biology in vitro ...
Malte Tiburcy +7 more
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Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle
Adult skeletal muscle possesses a remarkable regenerative ability that is dependent on satellite cells. However, skeletal muscle is replaced by fatty and fibrous connective tissue in several pathological conditions.
Akiyoshi eUezumi +2 more
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Pax7 and myogenic progression in skeletal muscle satellite cells [PDF]
Skeletal muscle growth and regeneration are attributed to satellite cells - muscle stem cells resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells express the transcription factor Pax7 and when activated, coexpress Pax7 with MyoD. Most then proliferate, downregulate Pax7 and differentiate.
Zammit, Peter +6 more
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Protein Availability and Satellite Cell Dynamics in Skeletal Muscle
Human skeletal muscle satellite cells are activated in response to both resistance and endurance exercise. It was initially proposed that satellite cell proliferation and differentiation were only required to support resistance exercise-induced hypertrophy.
Baubak Shamim +2 more
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Skeletal muscle satellite cells cultured in simulated microgravity [PDF]
Satellite cells are postnatal myoblasts responsible for providing additional nuclei to growing or regenerating muscle cells. Satellite cells retain the capacity to proliferate and differentiate in vitro and, therefore, provide a useful model to study postnatal muscle development.
G, Molnar +3 more
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Skeletal muscle satellite cells are a class of undifferentiated mononuclear myogenic stem cells distributed between the myofibroblast and membrane basement.
Long Li +6 more
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Satellite cells from dystrophic muscle retain regenerative capacity
Duchenne muscular dystrophy is an inherited disorder that is characterized by progressive skeletal muscle weakness and wasting, with a failure of muscle maintenance/repair mediated by satellite cells (muscle stem cells).
Luisa Boldrin +2 more
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