Results 51 to 60 of about 1,364 (146)

A Novel Murine Model for the In Vivo Study of Transdermal Drug Penetration

The Scientific World Journal, 2012
Enhancement of the transdermal penetration of different active agents is an important research goal. Our aim was to establish a novel in vivo experimental model which provides a possibility for exact measurement of the quantity of penetrated drug.
Gábor Eros, Petra Hartmann, Szilvia Berkó, Eszter Csizmazia, Erzsébet Csányi, Anita Sztojkov-Ivanov, István Németh, Piroska Szabó-Révész, István Zupkó, Lajos Kemény   +9 more
doaj   +1 more source

Rapid body weight gain increases the risk of UV radiation–induced skin carcinogenesis in SKH-1 hairless mice [PDF]

Nutrition Research, 2008
Although it is well known that caloric restriction reduces the risk of chronic diseases including cancer, the role of weight gain in the development of UV light-induced tumors has not, to our knowledge, been investigated. In view of the increase in obesity worldwide, we asked the question whether there is any relationship between body weight gain and ...
Dinkova-Kostova, Albena T., Fahey, Jed W., Jenkins, Stephanie N., Wehage, Scott L., Talalay, Paul   +4 more
openaire   +3 more sources

Balneotherapeutic effects of high mineral spring water on the atopic dermatitis-like inflammation in hairless mice via immunomodulation and redox balance

BMC Complementary and Alternative Medicine, 2017
Background Atopic dermatitis (AD) is a chronic relapsing allergic inflammatory skin disease that currently affects millions of children and adults worldwide.
Johny Bajgai, Ailyn Fadriquela, Jesmin Ara, Rahima Begum, Md Faruk Ahmed, Cheol-Su Kim, Soo-Ki Kim, Kwang-Yong Shim, Kyu-Jae Lee   +8 more
doaj   +1 more source

Enzyme-Treated Zizania latifolia Ethanol Extract Protects from UVA Irradiation-Induced Wrinkle Formation via Inhibition of Lysosome Exocytosis and Reactive Oxygen Species Generation

Antioxidants, 2020
Ultraviolet A (UVA) is a risk factor for photoaging and wrinkle formation. Zizania latifolia is an herbaceous perennial plant. It contains many bioactive compounds such as tricin that show antioxidative and anti-inflammatory effects.
Mirae An, Hyungkeun Kim, Joo-Myung Moon, Hyun-Soo Ko, Paul Clayton, Young-Hee Lim   +5 more
doaj   +1 more source

Long‐term sub‐erythemal UVB exposure does not impact circadian rhythms in mice under standard and rotating shift light conditions

Photochemistry and Photobiology, Volume 101, Issue 6, Page 1429-1442, November/December 2025.
Circadian disruption is a potential carcinogen, but the impact of environmental carcinogens on circadian rhythms is unclear. Here we evaluated the impact of chronic UVB exposure with environmental‐ and genetic‐induced circadian disruption on mouse rhythmic locomotor activity and clock gene expression. Created in BioRender. Cone, S.
Adam J. Greer, Sean J. Cone, Rachel Bernstein, Elizabeth Schuetz, Narayani Prasad Kar, Bala S. C. Koritala, Shobhan Gaddameedhi   +6 more
wiley   +1 more source

Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice [PDF]

Toxicological Sciences, 2008
Sulfur mustard (HD) is an alkylating and cytotoxic chemical warfare agent, which inflicts severe skin toxicity and an inflammatory response. Effective medical countermeasures against HD-caused skin toxicity are lacking due to limited knowledge of related mechanisms, which is mainly attributed to the requirement of more applicable and efficient animal ...
Neera, Tewari-Singh, Sumeet, Rana, Mallikarjuna, Gu, Arttatrana, Pal, David J, Orlicky, Carl W, White, Rajesh, Agarwal   +6 more
openaire   +2 more sources

Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations

Scientific Reports, 2017
Prolonged tomato consumption can mitigate ultraviolet (UV) light induced sunburn via unknown mechanisms. Dietary carotenoids distributed to skin are hypothesized to protect skin against UV-induced damage, although other phytochemicals may play a role. We
Jessica L. Cooperstone, Kathleen L. Tober, Ken M. Riedl, Matthew D. Teegarden, Morgan J. Cichon, David M. Francis, Steven J. Schwartz, Tatiana M. Oberyszyn   +7 more
doaj   +1 more source

Grape constituents for protection against photodamage to skin

Photochemistry and Photobiology, Volume 101, Issue 6, Page 1392-1401, November/December 2025.
Excessive exposure to solar ultraviolet radiation has a major negative impact on the health of skin. It causes sunburn, photoaging, keratinocyte carcinomas, and melanomas. Current methods of prevention have failed to stem the incidence of these adverse effects. Grapes are natural products that are being investigated as preventive agents that can impede
Yuri Kwon, Rubina Shafi, Allen Oak, Mohammad Athar, Andrzej Slominski, Craig A. Elmets   +5 more
wiley   +1 more source

Managing infectious aerosols to counter engineered pandemics: Current recommendations and future research

Risk Analysis, Volume 45, Issue 10, Page 3045-3078, October 2025.
Abstract In the increasingly likely event of an engineered‐virus outbreak or pandemic of catastrophic potential, managing infectious aerosols to reduce transmission will be crucial. Now is the time to start preparing our buildings, public opinion, and regulatory environments for the infectious aerosol management interventions necessary to protect the ...
Adam Lerner, Gediminas Mainelis, William Hallman, Howard Kipen, Monica Magalhaes, Brian Buckley, José Guillermo Cedeño Laurent, Nir Eyal   +7 more
wiley   +1 more source

Cactus cladodes (Opuntia humifusa) extract minimizes the effects of UV irradiation on keratinocytes and hairless mice

Pharmaceutical Biology, 2017
Context: Cactus cladodes [Opuntia humifusa (Raf.) Raf. (Cactaceae)] is one of the cactus genera, which has long been used as a folk medicine for skin disorders.
Kyungmi Park, Hyeon-Son Choi, Yang Hee Hong, Eun Young Jung, Hyung Joo Suh   +4 more
doaj   +1 more source