Results 71 to 80 of about 9,404,832 (356)

Neurocosmetics in Skincare—The Fascinating World of Skin–Brain Connection: A Review to Explore Ingredients, Commercial Products for Skin Aging, and Cosmetic Regulation

open access: yesCosmetics, 2021
The “modern” cosmetology industry is focusing on research devoted to discovering novel neurocosmetic functional ingredients that could improve the interactions between the skin and the nervous system.
V. Rizzi, J. Gubitosa, P. Fini, P. Cosma
semanticscholar   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

A New Approach toward the Management of Patients with Premature Skin Aging Using the Predictor Effect

open access: yesCosmetics, 2023
Our study aimed to develop a comprehensive approach to the management of patients with involutional skin changes, considering the predictors of premature skin aging.
Nikolai N. Potekaev   +8 more
doaj   +1 more source

Caring for Aging Skin

open access: yesAJN, American Journal of Nursing, 2018
This article is part of a series, Supporting Family Caregivers: No Longer Home Alone, published in collaboration with the AARP Public Policy Institute. Results of focus groups, conducted as part of the AARP Public Policy Institute's No Longer Home Alone video project, supported evidence that family caregivers aren't given the ...
Kirkland-Kyhn, Holly   +3 more
openaire   +5 more sources

Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis

open access: yesnpj Aging and Mechanisms of Disease, 2021
Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during human skin ...
C. Rübe   +7 more
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The role of peroxisome proliferator-activated receptor-coactivator-1 gene in skin aging

open access: yesJournal of Research in Medical Sciences, 2016
Skin aging is a continuous process that exhibits fine and deep wrinkles, thin and transparent skin, loss of underlying fat, dry skin and itch, following decreased collagen and elastin synthesis.
Shahrzad Aghaei   +2 more
doaj   +1 more source

Narrative Review: Herbal Nanocosmetics for Anti Aging

open access: yesJPSCR: Journal of Pharmaceutical Science and Clinical Research, 2023
Skin aging is a complex biological process caused by intrinsic and extrinsic factors. There are various approaches to preventing skin aging, one of which is using herbal nanocosmetics. This narrative review aims to determine the natural ingredients, type
Prilyano Garcella   +2 more
doaj   +1 more source

Estrogens and aging skin [PDF]

open access: yesDermato-Endocrinology, 2013
Estrogen deficiency following menopause results in atrophic skin changes and acceleration of skin aging. Estrogens significantly modulate skin physiology, targeting keratinocytes, fibroblasts, melanocytes, hair follicles and sebaceous glands, and improve angiogenesis, wound healing and immune responses.
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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