Results 191 to 200 of about 641,694 (264)

Federated learning for privacy-preserving skin cancer classification using deep neural networks. [PDF]

Front Oncol
Alfalahi MAM, Karan O, Kurnaz S, Türkben AK.   +3 more
europepmc   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

Carbon Dot-Based Photodynamic Therapy for Clinical Treatment of Nonmelanoma Skin Cancer. [PDF]

Dermatol Pract Concept
Romero MP, Garzón-Romero CC, Cruz F, Verdugo C, Bastidas DM, Mendez KM, Cabrera F.   +6 more
europepmc   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Beyond the surface: a collaborative effort for free skin cancer screenings in an underserved community. [PDF]

BMC Public Health
Lovasz D, Kan B, Martin EA, Riva H, Oke A, Guevara A, Jimenez C, Box N, Terzian T, Rodriguez R, Kichena S, Ramirez F, Shaffer W, Hogg T, Chacon J.   +14 more
europepmc   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Near-Infrared Spectroscopy Combined With Skin Impedance for Detection of Skin Cancer in Primary Care. [PDF]

Skin Res Technol
Dragka MF, Löfstedt T, Falk M.
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Public Cognizance Concerning Skin Cancer in the Qassim Region of Saudi Arabia: A Cross-Sectional Study. [PDF]

Cureus
Ismail A, Albreah R, Alqarawi S, AlAsqah L, Almutairi W, Alharbi W, Al Shibl K, Alrumaih R.   +7 more
europepmc   +1 more source