Results 141 to 150 of about 12,047 (235)

T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett   +2 more
wiley   +1 more source

Evaluation of a human in vitro skin test for predicting drug hypersensitivity reactions

open access: yes, 2019
\ua9 2019 Elsevier Inc. The occurrence of drug hypersensitivity reactions (DHRs) following administration of low molecular weight (LMW) drugs is an important health concern.
Whritenour J   +7 more
core  

Datasheet1_Functional human skin explants as tools for assessing mast cell activation and inhibition.docx

open access: yes
Mast cells are activated through a variety of different receptors to release preformed granules and mediators synthesized de novo. However, the physiology and function of mast cells are not fully understood. Traditional studies of mast cell activation in
Tinuola Owolabi (18260533)   +6 more
core   +1 more source

Ocular surface disease in atopic dermatitis

open access: yesActa Ophthalmologica, Volume 104, Issue S291, Page S4-S28, June 2026.
ENGLISH SUMMARY Atopic keratoconjunctivitis (AKC) is a severe ocular surface disease (OSD) that significantly affects patients' quality of life and can lead to blindness. AKC is associated with atopic dermatitis (AD), a common chronic inflammatory skin disease affecting both children and adults.
Pernille May Hansen
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3321-3339, June 2026.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Identification of Yellow Advanced Glycation End Products in Human Skin

open access: yes
Skin yellowness is a hallmark of dull or unhealthy skin, particularly among Asians. Previous research has indicated a link between skin glycation and skin yellowness. However, the specific glycated chemicals contributing to yellowish skin appearance have
Tomohiro Hakozaki   +4 more
core   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

open access: yesInternational Journal of Cosmetic Science, Volume 48, Issue 3, Page 500-517, June 2026.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

The Effect of Myrtacine and Celastrol‐Enriched Extract on Cutibacterium acnes Extracellular Vesicles

open access: yesInternational Journal of Dermatology, Volume 65, Issue 6, Page 1215-1224, June 2026.
Myrtacine alone, Celastrol‐enriched extract alone, or the combination of both ingredients were added to the culture medium either before (preventive condition) or after (modulating condition) incubation with C. acnes IA1 extracellular vesicles (EVs) from healthy and acne skin in immortalized keratinocytes (HaCaT cells) and human skin explants.
Caroline T. Cheung   +7 more
wiley   +1 more source

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