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Effect of Ouabain on Growth of Skin Explants in Organotypic Culture
Bulletin of Experimental Biology and Medicine, 2013Organotypic culture was used to study the effects of glycoside ouabain and its aglycone ouaba-genin on the growth of skin explants from 10-12-day chicken embryos. The tested agents demonstrated dose-dependent inhibition of skin growth. The effective concentrations imply that ouabain and ouabagenin mediate their inhibitory effect on the skin growth via ...
V A, Penniyaynen +3 more
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Archives of dermatology, 1977
The pathogenic effect of the intercellular antibodies of pemphigus was studied by using organ culture of monkey skin. Skin explants that were grown on sera with intercellular antibody titers of 320 or greater fixed these antibodies within one day as demonstrated by direct immunofluorescence for IgG. None of the control sera gave such staining patterns.
J S, Deng +3 more
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The pathogenic effect of the intercellular antibodies of pemphigus was studied by using organ culture of monkey skin. Skin explants that were grown on sera with intercellular antibody titers of 320 or greater fixed these antibodies within one day as demonstrated by direct immunofluorescence for IgG. None of the control sera gave such staining patterns.
J S, Deng +3 more
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Novel predictive assay for contact allergens using human skin explant cultures.
The American journal of pathology, 1996Contact allergens sensitize the immune system by the binding to and subsequent activation of Langerhans cells (LCs), the antigen-presenting cells of the skin. At present, new chemicals are usually tested for their contact allergenicity in animal models.
Pistoor, F. H. +6 more
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Three-Dimensional Human Epidermal Skin Models and Skin Explants
2014Hans-Werner Vohr, Eckhard Heisler
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Human skin explant model for Staphylococcus aureus vaccine research
2018Staphylococcus aureus is a major human pathogen and a member of the human skin microbiota. It is capable of infecting nearly every human tissue to cause a wide spectrum of disease that includes skin and soft tissue infection, infective endocarditis, toxic shock syndrome, necrotizing pneumonia, and osteomyelitis. The success of S.
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CRYOTOLERANCE OF SUPEROXYGENATED HUMAN SKIN EXPLANTS.
Surgical forum, 1996H B, BARNER +3 more
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