Results 1 to 10 of about 62,571 (334)

Influence of Lactobacillus Biosurfactants on Skin Permeation of Hydrocortisone [PDF]

Pharmaceutics, 2021
One of the most widely used strategies to improve drug diffusion through the skin is the use of permeation enhancers. The aim of this work was to investigate the effect of two biosurfactants (BS), produced by Lactobacillus crispatus BC1 and Lactobacillus
Angela Abruzzo, Carola Parolin, Elisa Corazza, Barbara Giordani, Massimiliano Pio di Cagno, Teresa Cerchiara, Federica Bigucci, Beatrice Vitali, Barbara Luppi   +8 more
doaj   +6 more sources

IAM Chromatographic Models of Skin Permeation. [PDF]

Molecules, 2022
Chromatographic retention factor log kIAM obtained from IAM HPLC chromatography with buffered aqueous mobile phases and calculated molecular descriptors (surface area—Sa; molar volume—VM; polar surface area—PSA; count of freely rotable bonds—FRB; H-bond acceptor count—HA; energy of the highest occupied molecular orbital—EHOMO; energy of the lowest ...
Sobańska AW, Brzezińska E.
europepmc   +4 more sources

Development and Characterisation of a Topical Methyl Salicylate Patch: Effect of Solvents on Adhesion and Skin Permeation [PDF]

Pharmaceutics, 2022
The advent of skin patch formulation design and technology has enabled the commercialisation of methyl salicylate (MS) as a topical patch. However, the most fundamental aspect of skin permeation is unknown at present.
Soo Chin Yeoh, Poh Lee Loh, Vikneswaran Murugaiyah, Choon Fu Goh   +3 more
doaj   +2 more sources

HuskinDB, a database for skin permeation of xenobiotics. [PDF]

Sci Data, 2020
AbstractSkin permeation is an essential biological property of small organic compounds our body is exposed to, such as drugs in topic formulations, cosmetics, and environmental toxins. Despite the limited availability of experimental data, there is a lack of systematic analysis and structure.
Stepanov D, Canipa S, Wolber G.
europepmc   +4 more sources

Kombucha as a Potential Active Ingredient in Cosmetics—An Ex Vivo Skin Permeation Study [PDF]

Molecules
Kombucha is a non-alcoholic beverage, that is increasingly used in the cosmetic industry. The available literature reports the positive effects of kombucha on the skin, in particular its antioxidant action. However, there is a lack of information on skin
Karolina Jakubczyk, Anna Nowak, Anna Muzykiewicz-Szymańska, Łukasz Kucharski, Kinga Szymczykowska, Katarzyna Janda-Milczarek   +5 more
doaj   +2 more sources

Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes [PDF]

Pharmaceutics, 2021
The steady improvement and optimization of transdermal permeation is a constant and challenging pharmaceutical task. In this study the influence of poly(lactide-co-glycolide) (PLGA) nanoparticles on the dermal permeation of the anti-inflammatory drug ...
Javiana Luengo, Marc Schneider, Anna M. Schneider, Claus-Michael Lehr, Ulrich F. Schaefer   +4 more
doaj   +2 more sources

Quantitative Structure-Permeation Relationships (QSPeRs) to Predict Skin Permeation: A Critical Evaluation [PDF]

Pharmaceutical Research, 2004
Development of reliable mathematical models to predict skin permeability remains a challenging objective. This article examines some of the existing algorithms and critically evaluates their statistical relevance.Complete statistics were recalculated for a number of published models using a stepwise multiple regression procedure.
Sandrine Geinoz, Richard H. Guy, Bernard Testa, Pierre‐Alain Carrupt   +3 more
openalex   +5 more sources

Photodynamic Therapy as a Novel Therapeutic Modality Applying Quinizarin-Loaded Nanocapsules and 3D Bioprinting Skin Permeation for Inflammation Treatment [PDF]

Pharmaceuticals
Skin inflammation associated with chronic diseases involves a direct role of keratinocytes in its immunopathogenesis, triggering a cascade of immune responses.
Stéphanie R. do Amaral, Camila F. Amantino, Aleksandar Atanasov, Stefanie Oliveira Sousa, Richard Moakes, Sonia Maria Oliani, Liam M. Grover, Fernando L. Primo   +7 more
doaj   +2 more sources

Skin Permeation Enhancement of Diclofenac by Fatty Acids [PDF]

Drug Delivery, 2008
This study systematically investigated the enhancing effect of fatty acids on the skin permeation of diclofenac. The fatty acids were evaluated in terms of their carbon-chain length, the degree of unsaturation, and their functional groups. The rat-skin permeation rates of diclofenac, saturated in propylene glycol (PG) containing 1% (w/v) fatty acid ...
M. Kim, Hea-Jeong Doh, Min-Koo Choi, Suk‐Jae Chung, Chang‐Koo Shim, Dae‐Duk Kim, Jung Sun Kim, Chul-Soon Yong, Han-Gon Choi   +8 more
openalex   +4 more sources

The Complementary Role of ToF-SIMS in the Assessment of Imiquimod Permeated into the Skin from a Microemulsion Dosage Form

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2019
The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques.
Mohammed Hussain Al-Mayahy, Maria Marlow, David J. Scurr   +2 more
doaj   +3 more sources