Results 11 to 20 of about 1,692,764 (393)
HuskinDB, a database for skin permeation of xenobiotics [PDF]
Scientific Data, 2020 AbstractSkin permeation is an essential biological property of small organic compounds our body is exposed to, such as drugs in topic formulations, cosmetics, and environmental toxins. Despite the limited availability of experimental data, there is a lack of systematic analysis and structure.
Stepanov, Dmitri +2 more
openaire +3 more sources
Hydrogel increases diclofenac skin permeation and absorption [PDF]
Biopharmaceutics & Drug Disposition, 2019 AbstractPurposeTopical nonsteroidal anti‐inflammatory drug formulations are used commonly to treat musculoskeletal pain and inflammation. Drug properties and formulation composition are the primary determinants of the transdermal drug delivery rate. The ex vivo transdermal flux through human skin of three topical diclofenac formulations was compared ...
Eleonore Haltner‐Ukomadu +3 more
openaire +3 more sources
Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities
Pharmaceutics, 2020 The transdermal route of drugs has received increased attention in recent years due to numerous advantages over the oral and injectable routes, such as avoidance of the hepatic metabolism, protection of drugs from the gastrointestinal tract, sustained ...
Rabin Neupane +4 more
doaj +2 more sources
Pharmaceutics, 2018 N-Palmitoyl-Glycine-Histidine (Pal-GH) is a novel low molecular weight gelator. In our previous report, ivermectin, a lipophilic drug, was effectively delivered to skin tissue after topical application with Pal-GH as a spray gel formulation, and a much ...
Sabrina Dahlizar +5 more
doaj +2 more sources
Pharmaceutics, 2018 The evaluation of UV-filter in vitro percutaneous absorption allows the estimation of the systemic exposure dose (SED) and the margin of safety (MoS) of sunscreen products.
Lucia Montenegro +3 more
doaj +2 more sources
Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The transdermal route of administration provides numerous advantages over conventional routes i.e., oral or injectable for the treatment of different diseases and cosmetics applications.
Yiqun Yu +3 more
openalex +2 more sources
Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives [PDF]
AMB Express, 2020 The aim of the study was to determine the antioxidant activity and assess the lipophilicity and skin penetration of eugenyl chloroacetate (EChA), eugenyl dichloroacetate (EDChA), and eugenyl trichloroacetate (ETChA).
Edyta Makuch +6 more
openalex +2 more sources
Development of essential oils as skin permeation enhancers: penetration enhancement effect and mechanism of action [PDF]
Pharmaceutical Biology, 2017 Context: Essential oils (EOs) have shown the potential to reversibly overcome the stratum corneum (SC) barrier to enhance the skin permeation of drugs.
Qiu-Dong Jiang +7 more
openalex +2 more sources
Enhanced Skin Permeation of Estradiol by Dimethyl Sulfoxide Containing Transdermal Patches
Pharmaceutics, 2021 Dimethyl sulfoxide is a well-known and widely used dermal penetration enhancer. Its incorporation in transdermal patches would be highly desirable; however, due to its volatility this is extremely challenging.
Anna Otterbach, A. Lamprecht
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Topical and transdermal delivery systems are of undeniable significance and ubiquity in healthcare, to facilitate the delivery of active pharmaceutical ingredients, respectively, onto or across the skin to enter systemic circulation.
Ana Gomes +4 more
semanticscholar +1 more source