Novel Nanocarriers for Targeted Topical Skin Delivery of the Antioxidant Resveratrol
Pharmaceutics, 2020 Resveratrol (RSV) is a potent lipophilic antioxidant with a low aqueous solubility. Novel nanoformulations have been successfully developed and evaluated to increase the potential of resveratrol as a skin targeting antioxidant.
Christofori M. R. R. Nastiti +4 more
doaj +1 more source
The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]
, 2010 In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Ackermann, K. +4 more
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Mathematical Model to Predict Skin Concentration after Topical Application of Drugs
Pharmaceutics, 2013 Skin permeation experiments have been broadly done since 1970s to 1980s as an evaluation method for transdermal drug delivery systems. In topically applied drug and cosmetic formulations, skin concentration of chemical compounds is more important than ...
Hiroaki Todo +3 more
doaj +1 more source
Human skin in vitro permeation of bentazon and isoproturon formulations with or without protective clothing suit [PDF]
, 2013 Skin exposures to chemicals may lead, through percutaneous permeation, to a significant increase in systemic circulation. Skin is the primary route of entry during some occupational activities, especially in agriculture. To reduce skin exposures, the use
Baldi, Isabelle +7 more
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Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]
, 2018 Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José +6 more
core +1 more source
Temperature influencing permeation pattern of alfuzosin: An investigation using DoE
Medicina, 2015 Background and objective: There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement.
Satyanarayan Pattnaik +4 more
doaj +1 more source
Current Status of Amino Acid-Based Permeation Enhancers in Transdermal Drug Delivery
Membranes, 2021 Transdermal drug delivery (TDD) presents many advantages compared to other conventional routes of drug administration, yet its full potential has not been achieved.
Rui Pereira +4 more
doaj +1 more source
Effects of precipitation conditions on the membrane morphology and permeation characteristics [PDF]
, 2009 [[abstract]]The permeability and permselectivity of asymmetric and particulate membranes towards glucose and proteins of various molecular sizes were studied.
Lin, Dong-tsamn
core +1 more source
Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]
, 2019 © 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria +5 more
core +2 more sources
Pharmaceutics, 2018 N-Palmitoyl-Glycine-Histidine (Pal-GH) is a novel low molecular weight gelator. In our previous report, ivermectin, a lipophilic drug, was effectively delivered to skin tissue after topical application with Pal-GH as a spray gel formulation, and a much ...
Sabrina Dahlizar +5 more
doaj +1 more source