Results 21 to 30 of about 1,692,764 (393)
Development and characterization of niosomal gel of fusidic acid: in-vitro and ex-vivo approaches
Designed Monomers and Polymers, 2022 Niosomes are multilamellar vesicles that efficiently deliver active substance into skin systemic circulation or skin layers. They are used in topical drug delivery system to enhance the skin permeation of active substance. So, the prime objective of this
Muhammad Khurram Waqas +9 more
doaj +1 more source
Pharmaceutics, 2023 Acyclovir (ACV) controls cutaneous herpes, genital herpes, herpes keratitis, varicella zoster, and chickenpox. From previously reported ACV formulations, we continued to explore the permeation behavior of the optimized ACV loaded optimized ethosome ...
Afzal Hussain +5 more
doaj +1 more source
Pharmaceuticals, 2020 Cannabidiol (CBD) is a non-psychoactive cannabinoid isolated from Cannabis sativa which, given its claimed beneficial properties and therapeutic potential, has lately aroused considerable attention from the scientific community.
A. Casiraghi +4 more
semanticscholar +1 more source
Molecular mechanism of the skin permeation enhancing effect of ethanol: a molecular dynamics study
RSC Advances, 2020 Ethanol is widely used in various pharmaceutical and cosmetic formulations in order to enhance skin penetration of active ingredients. While it is well known that ethanol partitions into the skin and enhances the permeation of both polar and nonpolar ...
Rakesh Gupta +3 more
semanticscholar +1 more source
Transdermal Permeation of Drugs in Various Animal Species
Pharmaceutics, 2017 Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and effect of topically-applied drugs by measuring its skin permeation and concentration. However, ethical considerations are the major problem for using human skin
Hiroaki Todo
doaj +1 more source
Enhancement of ibuprofen solubility and skin permeation by conjugation with l-valine alkyl esters
RSC Advances, 2020 New ibuprofen derivatives were made via conjugation with l-valine alkyl esters (ValOR), where R was changed from an ethyl to a hexyl group. The ionic structure was confirmed using NMR and FTIR.
E. Januś +6 more
semanticscholar +1 more source
Pharmaceutics, 2022 Infantile hemangiomas (IH) leave sequelae after involution. Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties.
Shih-Jen Chang +7 more
doaj +1 more source
Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]
, 2019 © 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria +5 more
core +2 more sources
Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]
, 2018 Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José +6 more
core +1 more source
Mathematical Model to Predict Skin Concentration after Topical Application of Drugs
Pharmaceutics, 2013 Skin permeation experiments have been broadly done since 1970s to 1980s as an evaluation method for transdermal drug delivery systems. In topically applied drug and cosmetic formulations, skin concentration of chemical compounds is more important than ...
Hiroaki Todo +3 more
doaj +1 more source