Results 71 to 80 of about 1,642,164 (380)

Vitamin D and Pigmented Skin [PDF]

Nutrients, 2022
The default supply of vitamin D3 to humans is its endogenous production in UV-B-exposed skin [...]
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Assessment of melanogenesis in a pigmented human tissue-cultured skin equivalent

Indian Journal of Dermatology, 2019
Background: Organotypic tissue-cultured skin equivalents are used for a broad range of applications either as possible substitute for animal tests or for transplantation in patient-centered care.
Nadja Nicole Zoller, Matthias Hofmann, Manuel Butting, Igor Hrgovic, Jürgen Bereiter-Hahn, August Bernd, Roland Kaufmann, Stefan Kippenberger, Eva Valesky   +8 more
doaj   +1 more source

Frontiers in Pigment Cell and Melanoma Research

, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca, Bosenberg, Marcus W., Box, Neil F., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Filipp, Fabian V., Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Poole, Caroline Le, Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S.   +26 more
core   +1 more source

Determination of melanin types and relative concentrations: an observational study using a non-invasive inverse skin reflectance analysis [PDF]

, 2014
Objective: Melanin is a major skin colour pigment that made up of eumelanin (the dark brown–black colour) and pheomelanin (the light red–yellow colour) pigments.
Alerstam, Bird, Burgess, Fitzpatrick, Gemert, Gillbro, Hani, Hani, Hani, Karsten, Kim, Lin, Parsad, Serup, Thody, Villarama, Yamaguchi, Zhong   +17 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Comprehensive analysis of lncRNAs modified by mA methylation in sheep skin [PDF]

Animal Bioscience
Objective N6-methyladenosine (m6A) is the most prevalent methylation of mRNA and plays crucial roles in various physiological processes, including pigmentation.
Jinzhu Meng, Jianping Li, Yuanyuan Zhao
doaj   +1 more source

A rare case of melanosis of the hard palate mucosa in a patient with chronic myeloid leukemia [PDF]

, 2015
Imatinib Mesylate, also known as Gleevec or ST1-571, is a tyrosine-kinase inhibitor used as the gold standard medication for the chronic myeloid leukemia (CML); Imatinib has indeed deeply revolutionized the CML therapy allowing most patients to have a ...
Bosco, Daniela, Fantozzi, Paolo Junior, Palaia, Gaspare, Romeo, Umberto, Tenore, Gianluca   +4 more
core   +3 more sources

Impact of Iron-Oxide Containing Formulations Against Visible Light-Induced Skin Pigmentation in Skin of Color Individuals.

Journal of Drugs in Dermatology, 2020
Visible light (400-700nm), which contributes to 45% of solar radiation, contributes to skin darkening and worsening of dyschromias, particularly in individuals with Fitzpatrick skin phototypes III and higher.
H. Dumbuya, P. Grimes, S. Lynch, Kaili Ji, M. Brahmachary, Q. Zheng, C. Bouez, J. Wangari-Talbot   +7 more
semanticscholar   +1 more source

Inflammatory Response‐Inspired Thermochromic Shield for Pneumatic Structures

Advanced Engineering Materials, EarlyView.
A thermochromic shield for pneumatic structures is developed, using anhydrous sodium acetate powder and thermochromic pigment‐included solution. In this shield composed of three layers, the exothermic and thermochromic reactions, followed by the mixture of both components, occur promptly with an incident of penetrating damage as a sign of initial ...
Hyun Jae Lee, Ryuma Niiyama
wiley   +1 more source