Results 81 to 90 of about 16,012,863 (396)

Application of modern immunological methods in the diagnosis of tuberculosis in HIV-infected patients

Журнал инфектологии, 2015
Combination of TB and HIV-infection is still the most nowadays important problem, and it connects not only with steady growth of HIV infection, but with difficulties in TB diagnosis.
A. A. Starshinova, A. M. Panteleev, E. V. Vasil’eva, V. V. Manina, M. V. Pavlova, N. V. Sapozhnikova   +5 more
doaj   +1 more source

Allergologische Diagnostik von Überempfindlichkeitsreaktionen auf Arzneimittel [PDF]

, 2008
Drug hypersensitivity reactions have to be tested to identify the culprit substance. The history includes the general information and specific data concerning used drugs, the classification and circumstances of the reaction.
Aberer, Werner, Bircher, Andreas J., Brehler, Randolph, Brockow, Knut, Dickel, Heinrich, Fuchs, Thomas, Hertl, Michael, Merk, Hans F., Mockenhaupt, Maja, Pfaar, Oliver, Przybilla, Bernhard, Ring, Johannes, Sachs, Bernhardt, Vieluf, Dieter, Wedi, Bettina, Worm, Margitta, Zuberbier, Torsten   +16 more
core   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Effect of stressed skin action on the behaviour of cold-formed steel portal frames [PDF]

, 2015
This paper describes a series of six full-scale laboratory tests conducted on cold-formed steel portal frame buildings in order to investigate the effects of joint flexibility and stressed skin diaphragm action.
Lawson, R. M., Lim, J. B. P., Macleod, I.A., Wrzesien, A. M., Xu, Y.   +4 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma [PDF]

, 2014
Background: Recent studies suggest that Staphylococcus aureus enterotoxin sensitization is a risk factor for asthma. However, there is a paucity of epidemiologic evidence on adult-onset asthma in community-based populations.
Bachert, Claus, Chang, Yoon-Seok, Cho, Sang-Heon, Choi, Min-Ho, Kang, Hye-Ryun, Kim, Sae-Hoon, Lim, Min Kyung, Min, Kyung-Up, Park, Heung-Woo, Song, Woo-Jung, Tomassen, Peter, Yun, E Hwa   +11 more
core   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Stability of diluted chlorhexidine for skin testing in drug allergy evaluations

Journal of Allergy and Clinical Immunology: Global
Background: Chlorhexidine gluconate (CHX), a common cause of perioperative anaphylaxis, is frequently used for skin testing in allergy evaluations. Although CHX’s maximal nonirritating concentrations are known, the stability of its dilutions for skin ...
Divya Shah, MD, Gabriel Cojuc-Konigsberg, BS, Stacy D. Brown, PhD, Sergio E. Chiarella, MD, Gerald W. Volcheck, MD, Hirohito Kita, MD, Lene H. Garvey, MD, PhD, Alexei Gonzalez-Estrada, MD   +7 more
doaj   +1 more source

Histoplasmin and paracoccidioidin skin reactivity in infantile population of Northern Argentina Reatividade cutânea à histoplasmina e paracoccidioidina na população infantil do norte da Argentina

Revista do Instituto de Medicina Tropical de São Paulo, 1996
In order to estimate ages at which etiological agents of systemic mycoses initiate infection, histoplasmin and paracoccidioidin skin tests were performed in 344 children of both sexes, between 2 and 15 years old.
Magdalena Mangiaterra, José Alonso, Miria Galvan, Gustavo Giusiano, Jorge Gorodner   +4 more
doaj   +1 more source