Results 11 to 20 of about 280,497 (114)

Editorial [PDF]

, 2011
Editorial do v. 15, n.
Asphe, RHE
core   +12 more sources

Effect of Melatonin on Psoriatic Phenotype in Human Reconstructed Skin Model. [PDF]

Biomedicines, 2022
Psoriasis is an inflammatory and auto-immune skin-disease characterized by uncontrolled keratinocyte proliferation. Its pathogenesis is not still fully understood; however, an aberrant and excessive inflammatory and immune response can contribute to its ...
Scuderi SA, Cucinotta L, Filippone A, Lanza M, Campolo M, Paterniti I, Esposito E.   +6 more
europepmc   +2 more sources

Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts

, 2018
Assessment of skin irritation is an essential component of the safety evaluation of medical devices. OECD Test Guideline 439 describes the use of reconstructed human epidermis (RhE) as an in vitro test system for classification of skin irritation by neat
권재성, 김광만
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Apresentação [PDF]

, 2012
Apresentação do n.
Asphe, RHE
core   +4 more sources

Skin and eye irritation assessment of oil palm (Elaeis guineensis) leaf extract for topical application [PDF]

, 2018
Many types of phytochemicals have been found to be present in oil palm leaf and could potentially be used as functional ingredients for skincare product. However, as of today, there is no published report on hazard identification and safety assessment of
Nor Zuliana Yusof, Abd Gani, Siti Salwa, Yusof, Nor Zuliana, Zafarizal Aldrin Azizul Hasan, Zainab Idris, Siti Salwa Abd Gani, Azizul Hasan, Zafarizal Aldrin, Idris, Zainab   +7 more
core   +1 more source

The use of reconstructed human epidermis for skin absorption testing

, 2022
S.161-187A formal validation study was performed, in order to investigate whether the commercially available reconstructed human epidermis (RHE) models, EPISKIN (R), EpiDerm (TM) and SkinEthic (R), are suitable for in vitro skin absorption testing.
Kamp, H., Schäfer, U., Kaca, M., Bock, U., Haltner-Ukomadu, E., Vuia, A., Düsing, H.-J., Netzlaff, F., Niedorf, F., Mehling, A., Schreiber, S., Hoffmann, C., Kersen, S., Schmidt, E., Kietzmann, M., Müller-Goymann, C., Lehr, C.-M., Diembeck, W., Gamer, A., Spielmann, H., Krächter, H.-U., Liebsch, M., Korting, H.C., Weimer, M., Rübbelke, M.K., Schäfer-Korting, M.   +25 more
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Skin concentrations of topically applied substances in reconstructed human epidermis (RHE) compared with human skin using in vivo confocal Raman microscopy [PDF]

, 2015
Detailed knowledge about the skin concentration of topically applied substances is important to understand their local pharamcological activity. In particular since in vitro models of reconstructed human epidermis are increasingly used as models for ...
Adlhart, Christian, Morf, Fabienne, Fleischli, Franziska D., Fleischli, Franziska, Fleischli FD, Morf F, Adlhart C   +6 more
core   +1 more source

ESAC Opinion on the SkinEthic™ Human Corneal Epithelium (HCE) Eye Irritation Test (EIT) [PDF]

, 2016
ESAC, the EURL ECVAM Scientific Advisory Committee, advises EURL ECVAM on scientific issues. Its main role is to conduct independent peer review of validation studies of alternative test methods and to assess their scientific validity for a given purpose.
KIRKLAND David, CARMICHAEL Neil, CLEWELL III Harvey, LEHR Claus-Michael, VIEGAS BARROSO Joao Filipe, SESARDIC Thea, NAVAS Jose M, KEJLOVÁ Kristina, KOPP-SCHNEIDER Annette, ROGGEN Erwin, KRÄTKE Renate, COSTA Lucio, RICHMOND Jon, ALLEN Dave, LIM Kyung-Min, BORLAK Jürgen, PIERSMA Aldert   +16 more
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The EURL ECVAM - Cosmetics Europe prospective validation study of Reconstructed human Cornea-like Epithelium (RhCE)-based test methods for identifying chemicals not requiring classification and labelling for serious eye damage/eye irritation: Validation Study Report [PDF]

, 2014
A prospective validation study of two Reconstructed human Tissue-based in vitro test methods (EpiOcular™ EIT and SkinEthic™ HCE) was conducted by EURL ECVAM and Cosmetics Europe to evaluate their usefulness to identify chemicals as either not classified ...
ESKES Chantra, RUBINGH Carina, ZUANG Valerie, VIEGAS BARROSO Joao Filipe, MCNAMEE Pauline, FREEMAN Stuart, SCHAEFFER Michael Wilhelm, ALÉPÉE Nathalie, COLE Thomas, PFANNENBECKER Uwe, REUS Astrid, LISKA Roman   +11 more
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Stratum corneum architecture of reconstructed human skin models monitored by fluorescent confocal laser scanning microscopy

, 2007
Fluorescence confocal scanning laser microscopy (CLSM) using a handheld scanner, was performed to visualize the microscopic architecture of stratum corneum (SC) of the three reconstructed human epidermal (RHE) models: EpiDermTM (MatTek Corporation ...
Kandarova, H., Liebsch, M., Richter, H., Lademann, J.   +3 more
core   +1 more source