Results 21 to 30 of about 280,497 (114)
Alternative test methods often use prediction models (PMs) for converting endpoint measurements into predictions. Two PMs are used for the skin corrosion tests (SCTs) of the OECD Test Guideline No. 431 (TG 431).
Griesinger, Claudius +5 more
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Prevalidation study on testing percutaneous absorption via reconstructed human epidermis.
§I NTRODUCTION: Toxicological testing is of increasing importance for risk analysis. The recently approved OECD-guideline 428 and guidance document 28 standardise experiments on in vitro percutaneous absorption using human and animal skin.
Kaca,M. +14 more
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KARAKTERISTIK PESERTA DIDIK DALAM PENDIDIKAN ISLAM TELAAH PEMIKIRAN KH. HASYIM ASY’ARI [PDF]
KH. Mohammad Hasyim Asy’ari thought about the student’s ethic can be classified into three categories (a) The student’s ethic to their selves. Such as, fixing their aim in studying, serious in studying, having qona’ah, can manage the time, wara’
Fathorrozy, Mad Sa’i
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Skin irritation tests using reconstructed human epidermis (RhE) employ viability as an endpoint, but color interference or borderline results are often problematic. We examined whether the cytology of cells from treated RhE could determine skin irritancy.
임경민
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Currently, two reconstructed human skin models, EpiDerm and EPISKIN are being evaluated in an ECVAM skin irritation validation study. A common skin irritation protocol has been developed, differing only in minor technical details for the two models.
Traue, D. +10 more
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During the past ten years, a lot of attention has been paid to the development of in vitro tests that could substitute irritation studies employing animals.
Tornier,C. +9 more
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In 2002 the National Co-ordinators of OECD Test Guideline Programme (WNT) endorsed a New Draft Test Guideline TG 431 (Human Skin Model) for In Vitro Skin Corrosion Testing which was finally adopted in April 2004.
Remmele,M. +14 more
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Reconstructed human epidermis for skin absorption testing: Results of the German prevalidation study
Exposure to chemicals absorbed by the skin can threaten human health. In order to standardise the predictive testing of percutaneous absorption for regulatory purposes, the OECD adopted guideline 428, which describes methods for assessing absorption by ...
Kamp, H. +21 more
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A formal validation study was performed, in order to investigate whether the commercially available reconstructed human epidermis (RHE) models, EPISKIN®, EpiDermT and SkinEthic®, are suitable for in vitro skin absorption testing.
Kamp, H. +25 more
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Reconstructed human epidermis for assessment of percutaneous absorption in vitro a validation study
Titelblatt und Inhaltsverzeichnis Einleitung Material und Methoden Ergebnisse Diskussion Zusammenfassung LiteraturverzeichnisIn dieser Arbeit erfolgte die Charakterisierung der drei im Jahr 2002 kommerziell verfügbaren rekonstruierten humanen
Vuia, Alexander Gabriel
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