Results 91 to 100 of about 1,479 (176)

Influence of Genetic Polymorphisms in Prostaglandin E2 Pathway (COX-2/HPGD/SLCO2A1/ABCC4) on the Risk for Colorectal Adenoma Development and Recurrence after Polypectomy [PDF]

, 2016
OBJECTIVES: Deregulation of prostaglandin E2 (PGE2) levels reported in colorectal carcinogenesis contributes to key steps of cancer development. Our aim was to evaluate the influence of the genetic variability in COX-2/HPGD/SLCO2A1/ABCC4 PGE2 pathway ...
Marcos-Pinto, R., Pimentel-Nunes, P., Sousa, H., Brandão, C., Queirós, S., Medeiros, R., Galaghar, A., Pereira, C., Dinis-Ribeiro, M.   +8 more
core   +1 more source

Effects of pulpotomy using mineral trioxide aggregate on prostaglandin transporter and receptors in rat molars

Scientific Reports, 2017
Mineral trioxide aggregate (MTA) is a commonly used dental pulp-capping material with known effects in promoting reparative dentinogenesis. However, the mechanism by which MTA induces dentine repair remains unclear.
Naoto Ohkura, Naoki Edanami, Ryosuke Takeuchi, Aiko Tohma, Mariko Ohkura, Nagako Yoshiba, Kunihiko Yoshiba, Hiroko Ida-Yonemochi, Hayato Ohshima, Takashi Okiji, Yuichiro Noiri   +10 more
doaj   +1 more source

Supplementary Material for: Primary Hypertrophic Osteoarthropathy Mimicking Juvenile Idiopathic Arthritis: A Novel SLCO2A1 Mutation and Imaging Findings

, 2019
Primary hypertrophic osteoarthropathy (PHO), also known as pachydermoperiostosis, is a rare, multisystemic, autosomal recessive condition typically presenting with digital clubbing, osteoarthropathy, and various skin manifestations.
Karabulut H.G. (6851148), Torgutalp M (6851143), Durmaz C.D (6851145), Seifert W. (6851149), Turgay M. (6851153), Akkaya Z. (6851152), Horn D. (6851151)   +6 more
core   +1 more source

A rare cause of obscure gastrointestinal bleeding: Chronic enteropathy associated with SLCO2A1 mutation in a case from India

International Journal of Gastrointestinal Intervention
A 13-year-old boy presented with an 8-year history of repeated episodes of anemia. Laboratory investigations confirmed iron deficiency anemia due to occult blood loss from the gastrointestinal tract.
Shivani Chopra, Vikramaditya Rawat, Meghraj Ingle, Saiprasad Lad, Mit Shah, Deepak Sasikumar, Vinay Borkar, Yatin Lunagariya, Somraj Patil   +8 more
doaj   +1 more source

A Case Report of Pachydermoperiostosis by Multidisciplinary Diagnosis and Treatment

罕见病研究
A 20-year-old male patient presented to the Department of Dermatology of Peking Union Medical College Hospital with complaints of an 8-year history of facial scarring, swelling of the lower limbs, and a 4-year history of scalp thickening.
ZHANG Jie, ZHANG Yan, HUO Li, LYU Ke, WANG Tao, XIA Ze'nan, LONG Xiao, XU Kexin, WU Nan, YANG Bo, XIA Weibo, HU Rongrong, CHEN Limeng, LI Ji, HONG Xia, ZHANG Yan, ZUO Yagang   +16 more
doaj   +1 more source

A Complete Form of Pachydermoperiostosis Accompanied by a Pituitary Microadenoma

Clinical, Cosmetic and Investigational Dermatology, 2023
Yan Jing Chen, Li Li Department of Dermatology and Venereology, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Li Li, Department of dermatology and venereology, West China Hospital, Sichuan University,
Chen YJ, Li L
doaj  

Disposition of PGE₂ in the lung and BALF from WT and Slco2a1-/- mice.

, 2015
(A) Endogenous PGE2, PGF2α, and 15-keto PGE2 concentrations were analyzed using LC-MS/MS in lung homogenates of WT (open column) and Slco2a1-/- (closed column) mice.
Shin-ichi Akanuma (331229), Tomohiko Wakayama (29594), Ikumi Tamai (333356), Yuka Uetoko (731749), Ken-ichi Hosoya (331230), Takeo Nakanishi (333351), Reo Mimura (731748), Yoshitaka Hasegawa (731747), Hisakazu Komori (731750)   +8 more
core   +1 more source

Mutations in the prostaglandin transporter encoding gene SLCO2A1 Cause primary hypertrophic osteoarthropathy and isolated digital clubbing

, 2012
Digital clubbing is usually secondary to different acquired diseases. Primary hypertrophic osteoarthropathy (PHO) is a rare hereditary disorder with variable digital clubbing as the most prominent feature, subperiosteal new bone formation, and ...
Tueysuez, Beyhan, SPECKER, Christof, BROUWERS, AD, HORN, Denise, SEIFERT, Wenke, KUEHNISCH, Jirko   +5 more
core   +1 more source

Transcript abundance levels for AKT3, PTGS2, RAF1, SLCO2A1 and TLN1 for all treatments in endometrial samples from pregnant (P+) and non-pregnant (NP) mares.

, 2019
This figure contains the gene expression data for AKT3, PTGS2, RAF1, SLCO2A1 and TLN1. E = no treatment (control); EE = endometrium with an embryo in contact with the luminal side of the biopsy sample; EB = endometrium with beads in contact with the ...
K. M. Klohonatz (6425279), A. M. Hess (6425285), G. J. Bouma (6425288), J. E. Bruemmer (6425291), L. C. Nulton (6425282)   +4 more
core   +1 more source

Interleukin-6, tumor necrosis factor-alpha and receptor activator of nuclear factor kappa ligand are elevated in hypertrophic gastric mucosa of pachydermoperiostosis

, 2017
Pachydermoperiostosis (PDP) is a rare inherited multisystem disease characterized with digital clubbing, pachydermia and periostosis. Variants in either HPGD or SLCO2A1 that interrupt the prostaglandin E2 (PGE2) pathway have been shown to be involved in ...
Hui Huang, Yongjun Wang, Boda Wu, Xiaoliu Shi, Jianguang Tang, Yonggui Li, Yong Cao, Liangliang Fan, Zhiping Tan, Yi Jiang, Jianzhong Hu   +10 more
core   +1 more source