Results 91 to 100 of about 2,152 (193)

Safety and efficacy of cyclooxygenase-2 inhibition for treatment of primary hypertrophic osteoarthropathy: A single-arm intervention trial

Journal of Orthopaedic Translation, 2019
Background: Primary hypertrophic osteoarthropathy (PHO) is a rare disease involving joint, bone and skin. Two underlying genes responsible for this disease—hydroxyprostaglandin dehydrogenase (HPGD) and solute carrier organic anion transporter family ...
Lu Yuan, Ruo-xi Liao, Yuan-yuan Lin, Yan Jiang, Ou Wang, Mei Li, Xiao-ping Xing, Qian-qian Pang, Evelyn Hsieh, Wei-bo Xia   +9 more
doaj   +1 more source

Imaging Techniques and Differential Diagnosis for Inflammatory Bowel Disease

Journal of the Korean Society of Radiology, 2023
The two main types of inflammatory bowel disease (IBD) are Crohn’s disease and ulcerative colitis. Currently, when IBD is suspected, CT enterography is widely used as an initial imaging test because it can evaluate both the bowel wall and the outside ...
Kyoung Doo Song
doaj   +1 more source

Evaluation of hyponatremia among older adults exposed to selective serotonin reuptake inhibitors and thiazide diuretics

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 3, Page 169-176, March 2025.
Abstract Objective Hyponatremia is a common electrolyte disorder among older adults that can cause serious adverse effects. The purpose of this study was to assess the risk of hyponatremia with the concurrent use of selective serotonin reuptake inhibitors (SSRIs) and thiazide diuretics in an older population.
Trisha Matsuura, Abdelrahaman G. Tawfik, Kenechukwu C. Ben‐Umeh, Philip D. Hansten, Daniel C. Malone   +4 more
wiley   +1 more source

Histopathological study of the localization/distribution of Fusobacterium nucleatum in esophageal cancer

Pathology International, Volume 75, Issue 2, Page 82-91, February 2025.
We visualized F. nucleatum using FISH and identified different distribution patterns of F. nucleatum, highlighting the spot density of its presence in tumor tissues. F. nucleatum was identified more frequently in esophageal cancer tissues than in the normal epithelium. As tumor progression advanced, the area occupied by F.
Iku Sasaki‐Higashimoto, Fumiyoshi Fujishima, Hirotaka Ishida, Yusuke Taniyama, Yohei Ozawa, Tomohiro Nakamura, Naoki Nakaya, Chiaki Sato, Hiroshi Okamoto, Junichi Tsunokake, Atsushi Kunimitsu, Takeru Mozumi, Takashi Kamei, Takashi Suzuki   +13 more
wiley   +1 more source

Spontaneous Transformation of Murine Oviductal Epithelial Cells: A Model System to Investigate the Onset of Fallopian-Derived Tumors [PDF]

, 2015
High-grade serous carcinoma (HGSC) is the most lethal ovarian cancer histotype. The fallopian tube secretory epithelial cells (FTSECs) are a proposed progenitor cell type.
Daniel D. Lantvit, David A. Davis, Georgette Moyle-Heyrman, Jian-Jun Wei, Joanna E. Burdette, Michael P. Endsley, Subbulakshmi Karthikeyan   +6 more
core   +2 more sources

Induced Pluripotent Stem Cell‐Derived Parathyroid Organoids Resemble Parathyroid Morphology and Function

Advanced Science, Volume 11, Issue 43, November 20, 2024.
iPSC‐derived parathyroid organoids express PTH‐related markers at the protein and gene levels. The transplantation of parathyroid organoids into parathyroidectomized rats shows their functional activity and tissue integration capability. iPSC‐derived parathyroid organoids successfully release PTH both in vitro and in vivo.
Selinay Şenkal‐Turhan, Ezgi Bulut‐Okumuş, Muhterem Aydın, Neşe Başak Türkmen, Aslı Taşlıdere, Fikrettin Şahin, Şahin Yılmaz, Pınar Akkuş Süt, Ayşegül Doğan   +8 more
wiley   +1 more source

Single‐cell RNA‐seq in diabetic foot ulcer wound healing

Wound Repair and Regeneration, Volume 32, Issue 6, Page 880-889, November/December 2024.
Abstract Diabetic foot ulcer (DFU) is a chronic and serious complication of diabetes mellitus. It is mainly caused by hyperglycaemia, diabetic peripheral vasculopathy and diabetic peripheral neuropathy. These conditions result in ulceration of foot tissues and chronic wounds.
Yan Dong, Mengting Wang, Qianqian Wang, Xiaoliang Cao, Peng Chen, Zhenhua Gong   +5 more
wiley   +1 more source

Evaluation of a Chemiluminescent Enzyme Immunoassay for the Detection of Prostaglandin E‐Major Urinary Metabolite (PGE‐MUM)

Journal of Clinical Laboratory Analysis, Volume 38, Issue 19-20, October 2024.
We developed a chemiluminescent enzyme immunoassay (CLEIA), which can detect prostaglandin E‐major urinary metabolite (PGE‐MUM) with automated procedure in ~30 min. Here, we evaluated its analytical performance. This assay can precisely detect PGE‐MUM with good reproducibility and showed a good correlation with preceding radioimmunoassay (RIA ...
Jun Takagi, Kazushige Moriyama, Seiji Arihiro, Tomohiro Kato, Toshiyuki Sakurai, Masayuki Saruta, Mie Wakabayashi, Hidekazu Nasu, Noriko Katagiri, Shintaro Yagi   +9 more
wiley   +1 more source

A Case Report of Primary Hypertrophic Osteoarthropathy

罕见病研究
Primary hypertrophic osteoarthropathy(PHO) is a rare disease also known as pachydermoperiostosis. We reported a painless case whose diagnosis was confirmed by genetic test. A 24-year-old male presented a series of symptoms that first began at 14.
ZHAO Zongxuan, SUN Liying, CHEN Jia, WANG Yanyuan, CHEN Dan, ZUO Qingyao, DENG Wei, TIAN Wen   +7 more
doaj   +1 more source

Effects of Maternal Diabetes and Diet on Gene Expression in the Murine Placenta [PDF]

, 2022
Adverse exposures during pregnancy have been shown to contribute to susceptibility for chronic diseases in offspring. Maternal diabetes during pregnancy is associated with higher risk of pregnancy complications, structural birth defects, and ...
Kappen, Claudia, Kruger, Claudia, Michael Salbaum, J.   +2 more
core   +1 more source