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Sleeping sickness is a circadian disorder [PDF]

open access: yesNature Communications, 2018
African sleeping sickness is well known for the alterations of sleeping patterns, but it is not known how circadian biology is altered by the causative pathogen Trypanosoma brucei. Here the authors show T.
Filipa Rijo-Ferreira   +2 more
exaly   +3 more sources

Sleeping Sickness at the Crossroads [PDF]

open access: yesTropical Medicine and Infectious Disease, 2020
Human African trypanosomiasis (HAT; sleeping sickness) is a disease with truly historic dimensions [...]
Christian Burri
doaj   +2 more sources

Sleeping Sickness: A Tale of Two Clocks [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Sleeping sickness is caused by a eukaryotic unicellular parasite known to infect wild animals, cattle, and humans. It causes a fatal disease that disrupts many rhythmic physiological processes, including daily rhythms of hormonal secretion, temperature ...
Filipa Rijo-Ferreira   +3 more
doaj   +2 more sources

The Drugs of Sleeping Sickness: Their Mechanisms of Action and Resistance, and a Brief History [PDF]

open access: yesTropical Medicine and Infectious Disease, 2020
With the incidence of sleeping sickness in decline and genuine progress being made towards the WHO goal of eliminating sleeping sickness as a major public health concern, this is a good moment to evaluate the drugs that ‘got the job done’ ...
Harry P. De Koning
doaj   +2 more sources

Sleeping sickness [PDF]

open access: yesClinical Microbiology and Infection, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, is a vector-borne disease that flourishes in impoverished, rural parts of sub-Saharan Africa. It is caused by infection with the protozoan parasite Trypanosoma brucei and is transmitted by tsetse flies of the genus Glossina. The majority of cases are caused by T. b.
Malvy, D, Chappuis, François
  +15 more sources

Covid-19: Medicine and Colonialism, Past and Present

open access: yesJournal of Extreme Anthropology, 2022
This essay begins in the past, with the hope of developing a different way of thinking through the transformations of the present. Many commentators and media outlets have referred to the era of the Covid-19 pandemic as ‘unprecedented’, but there is ...
Toby Green
doaj   +1 more source

An Active Follow-up Strategy for Serological Suspects of Human African Trypanosomiasis with Negative Parasitology Set up by a Health Zone Team in the Democratic Republic of Congo

open access: yesTropical Medicine and Infectious Disease, 2020
Background: The World Health Organization aims for the elimination of Human African Trypanosomiasis (HAT) as a public health problem by 2020 and for full elimination (absence of new cases) by 2030.
Matthieu Nkieri   +6 more
doaj   +1 more source

African sleeping sickness [PDF]

open access: yesBMJ, 2008
Eflornithine should be the drug of choice for stage 2 disease, but resistance must be ...
Checchi, Francesco, Barrett, Michael P
openaire   +1 more source

Experiences of the one-health approach by the Uganda Trypanosomiasis Control Council and its secretariat in the control of zoonotic sleeping sickness in Uganda

open access: yesParasite Epidemiology and Control, 2020
Elimination of sleeping sickness from endemic countries like Uganda is key if the affected communities are to exploit the potential of the available human and livestock resources (production and productivity). Trypanosoma brucei rhodesiense, the parasite
C. Waiswa   +4 more
doaj   +1 more source

Should I get screened for sleeping sickness? A qualitative study in Kasai province, Democratic Republic of Congo. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
BACKGROUND: Control of human African trypanosomiasis (sleeping sickness) in the Democratic Republic of Congo is based on mass population active screening by mobile teams.
Alain Mpanya   +11 more
doaj   +1 more source

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