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Civil conflict and sleeping sickness in Africa in general and Uganda in particular
Conflict and war have long been recognized as determinants of infectious disease risk. Re-emergence of epidemic sleeping sickness in sub-Saharan Africa since the 1970s has coincided with extensive civil conflict in affected regions.
Berrang Ford Lea
doaj +1 more source
Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study. [PDF]
BACKGROUND:The polymerase chain reaction (PCR) has been proposed for diagnosis, staging and post-treatment follow-up of sleeping sickness but no large-scale clinical evaluations of its diagnostic accuracy have taken place yet.
Stijn Deborggraeve+7 more
doaj +1 more source
Late stage infection in sleeping sickness. [PDF]
At the turn of the 19(th) century, trypanosomes were identified as the causative agent of sleeping sickness and their presence within the cerebrospinal fluid of late stage sleeping sickness patients was described.
Hartwig Wolburg+10 more
doaj +1 more source
: The impact of war on the evolution of sleeping sickness in west-central Cote d'Ivoire [PDF]
International audienceTo evaluate the situation of sleeping sickness in west-central Cote d'Ivoire from 2000 to 2003, in view of the war which broke out in September 2002. Active surveys by medical teams and passive case detection. Between 2000 and 2003,
Courtin, Fabrice+7 more
core +3 more sources
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openaire +3 more sources
African trypanosomiasis is a disease caused by Trypanosoma brucei parasites with limited treatment options. Trypanosoma is unable to synthesize purines de novo and relies solely on their uptake and interconversion from the host, constituting purine ...
Fabian Hulpia+9 more
semanticscholar +1 more source
African sleeping sickness [PDF]
Eflornithine should be the drug of choice for stage 2 disease, but resistance must be ...
Francesco Checchi, Michael P. Barrett
openaire +2 more sources
Human African trypanosomiasis : current status and eradication efforts [PDF]
Epidemics of human African trypanosomiasis (HAT) in the 20th century led to millions of deaths. However, since the start of the twenty-first century, there is been a continued decline in the number of reported cases, due to increased investment and ...
Davis, Christopher+2 more
core +1 more source