Results 31 to 40 of about 19,704 (280)

Global stability analysis of the disease-free equilibrium state of a mathematical model of trypanosomiasis

open access: yesJournal of Applied Sciences and Environmental Management, 2019
The global stability analysis represents a compound failure, mechanism which provides lower calculated factors of safety. In this research, the global stability analysis was used to propose a mathematically model of the transmission dynamics and control
K.M. Bello   +4 more
doaj   +1 more source

A two-stage solution

open access: yeseLife, 2021
The parasite that causes African sleeping sickness can be transmitted from mammals to tsetse flies in two stages of its lifecycle, rather than one as was previously thought.
Fabien Guegan, Luisa Figueiredo
doaj   +1 more source

Reanalyzing the 1900–1920 Sleeping Sickness Epidemic in Uganda

open access: yesEmerging Infectious Diseases, 2004
Sleeping sickness has long been a major public health problem in Uganda. From 1900 to 1920, more than 250,000 people died in an epidemic that affected the southern part of the country, particularly the Busoga region.
E.M. Fèvre   +3 more
doaj   +1 more source

Implications of Heterogeneous Biting Exposure and Animal Hosts on Trypanosomiasis brucei gambiense Transmission and Control. [PDF]

open access: yesPLoS Computational Biology, 2015
The gambiense form of sleeping sickness is a neglected tropical disease, which is presumed to be anthroponotic. However, the parasite persists in human populations at levels of considerable rarity and as such the existence of animal reservoirs has been ...
Chris M Stone, Nakul Chitnis
doaj   +1 more source

Parasitic Protists: Diversity of Adaptations to a Parasitic Lifestyle

open access: yesMicroorganisms, 2022
Parasitic protists cause some of the most well-known human and animal diseases such as malaria, toxoplasmosis, amoebic meningitis, sleeping sickness, leishmaniosis, and diarrheal illness of protozoan origin (e [...]
Iva Kolářová   +2 more
doaj   +1 more source

Sleeping Sickness

open access: greenJournal of the Royal Army Medical Corps, 1908
openaire   +3 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The development of drugs for treatment of sleeping sickness: a historical review

open access: yesParasites & Vectors, 2010
Only four drugs are available for the chemotherapy of human African trypanosomiasis or sleeping sickness; Suramin, pentamidine, melarsoprol and eflornithine. The history of the development of these drugs is well known and documented. suramin, pentamidine
Steverding Dietmar
doaj   +1 more source

Home - About - Disclaimer - Privacy