Results 111 to 120 of about 911,787 (405)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Discrete Global Sliding Mode Control for Time-Delay Carbon Fiber Multilayer Diagonal Loom

open access: yesIEEE Access, 2017
In order to overcome the disadvantage that the dynamic sliding mode surface of the discrete global sliding mode control has a too long evolution time, a quick discrete global sliding mode control method is proposed.
Wei Liu, Guowei Xu, Xiuming Jiang
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Dynamic Sliding-Mode Control for T-S Fuzzy Singular Time-Delay Systems With ${H}_{\infty}$ Performance

open access: yesIEEE Access, 2019
In this paper, we propose a novel sliding-mode control for Takagi-Sugeno (T-S) fuzzy singular system with time-delay and mismatched uncertainties and disturbances.
Jiasheng Shi, Qingling Zhang
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Analysis of explicit and implicit discrete-time equivalent-control based sliding mode controllers [PDF]

open access: yes, 2013
Different time-discretization methods for equivalent-control based sliding mode control (ECB-SMC) are presented. A new discrete-time sliding mode control scheme is proposed for linear time-invariant (LTI) systems.
Acary, Vincent   +2 more
core   +2 more sources

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