Results 51 to 60 of about 58,768 (266)

A Comparative Experimental Study of Robust Sliding Mode Control Strategies for Underactuated Systems

IEEE Access, 2018
This paper presents a comprehensive comparative study for the tracking control of a class of underactuated nonlinear uncertain systems. A given nonlinear model of the underactuated system is, at first stage, transformed into an input output form and the ...
Sami Ud Din, Qudrat Khan, Fazal Ur Rehman, Rini Akmeliawanti   +3 more
doaj   +1 more source

Output feedback sliding mode control based on adaptive sliding mode disturbance observer

Measurement + Control, 2022
In this paper, an adaptive sliding mode disturbance observer is designed to counteract the disturbance actively. By designing the adaptive laws, the assumptions on the disturbance are relaxed in the proposed observer, its first derivative upper bound is ...
Chen Yunjun, Jiang Chao, Dong Jiuzhi, Zhao Zhanshan   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Optimization of EHA sliding mode controller based on spider wasp algorithm

Zhongguo Jianchuan Yanjiu
ObjectiveThis paper proposes using the Spider Wasp Optimization (SWO) algorithm to achieve precise position control of an electro-hydrostatic actuator (EHA) while reducing the parameter tuning difficulty of the EHA sliding mode controller and improving ...
Weibo LI, Hao ZHANG, Chenghu XU, Maojie ZHANG, Hualiang FANG   +4 more
doaj   +1 more source

Iterative sliding mode control strategy of robotic arm based on fractional calculus

Journal of Measurement Science and Instrumentation, 2021
In order to improve the control performance of industrial robotic arms, an efficient fractional-order iterative sliding mode control method is proposed by combining fractional calculus theory with iterative learning control and sliding mode control.
ZHANG Xin, LU Wenru, MIAO Zhongcui, JIANG Ziyun, ZHANG Jing   +4 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Adaptive Super-Twisting Algorithm-Based Nonsingular Terminal Sliding Mode Guidance Law

Journal of Control Science and Engineering, 2020
A nonsingular fast terminal sliding mode guidance law with an impact angle constraint is proposed to solve the problem of missile guidance accuracy and impact angle constraint for maneuvering targets.
Fang Yang, Kuanqiao Zhang, Lei Yu
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Integral sliding mode control for active suspension systems of half-vehicle model

Mechanical Engineering Journal, 2015
This paper proposes a design method of sliding mode controller with the robustness against actuator uncertainty for active suspension systems of half-vehicle model. The features of the proposed sliding mode controller are not to require any force sensors
Shigehiro TOYAMA, Fujio IKEDA
doaj   +1 more source