Results 31 to 40 of about 58,768 (266)

Global Terminal Sliding Mode Control With the Quick Reaching Law and Its Application

IEEE Access, 2018
In order to overcome the disadvantages of the conventional sliding mode reaching law, such as the large chattering and the slow convergence rate, an improved quick reaching law is proposed.
Chunbo Xiu, Penghui Guo
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sliding Mode Control of a Class of Hybrid-Switched Systems with Disturbances

Mathematics
This paper investigates the problem of sliding mode control for a class of hybrid switched systems with matching disturbances. Firstly, a sliding mode surface is designed, and the corresponding sliding mode equation for the switched system is derived ...
Jiaojiao Li, Yingying Wang, Jianyu Zhang
doaj   +1 more source

Quadratic feedback–based equivalent sliding mode control of wind turbine blade section based on rigid trailing-edge flap

Measurement + Control, 2019
Modeling of aeroelastic system of wind turbine blade section based on chordwise rigid trailing-edge flap has been investigated. The flutter suppression of blade section exhibiting flap-wise bending and twist deformation is performed by equivalent sliding
Ting-Rui Liu
doaj   +1 more source

Disturbance Observer-Based Control to Guarantee a Sliding Mode Without Sliding Mode Control

IEEE Access, 2023
This paper presents a novel disturbance observer (DOB)-based control method to prevent the deterioration of transient response due to disturbances. The proposed method uses sliding mode dynamics without a sliding mode control (SMC) structure and does not
Keonwoo Lee, Jaejun Cha, Seungkyu Park
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Sliding Mode Control of Servo Feed System Based on Fuzzy Reaching Law

Applied Sciences, 2023
An adaptive sliding mode control method based on the fuzzy exponential convergence law is proposed to solve the jitter problem caused by the sliding mode control of the servo-feed system and to improve the tracking performance of the system.
Chong-Li Huang, Tao Wang, Meng Li, Yang Yu   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Discrete Global Sliding Mode Control for Time-Delay Carbon Fiber Multilayer Diagonal Loom

IEEE Access, 2017
In order to overcome the disadvantage that the dynamic sliding mode surface of the discrete global sliding mode control has a too long evolution time, a quick discrete global sliding mode control method is proposed.
Wei Liu, Guowei Xu, Xiuming Jiang
doaj   +1 more source