Results 31 to 40 of about 10,008 (264)

THE SENTENCE PRODUCTION OF SLOW LEARNERS AND ITS IMPLICATION ON LEARNING: A CASE STUDY AT SDI MELATI NUSANTARA

open access: yesJurnal PAJAR (Pendidikan dan Pengajaran), 2020
Slow learner children have barriers in complex thinking processe especially in language. Low IQ levels craft them difficulties to identify sentence structure which result in the disruption of their sentence production process.
Wardatul Yunita Tikasari
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Development of gross motor skills and nutrition literacy among inclusive junior high school students

open access: yesPedagogy of Physical Culture and Sports
Background and Study Aim. Slow learners in inclusive junior high schools often face difficulties in developing gross motor skills and possess limited nutritional literacy.
Ngatman Ngatman   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Critical Thinking Skills of Slow Learners in Mathematical Problem-Solving: A Systematic Literature Review

open access: yesJournal of Mathematics Instruction, Social Research and Opinion
Although much research has highlighted slow learners' difficulties in learning mathematics, most studies have focused only on the final learning outcomes without delving into the thinking processes during problem-solving.
Sulfiati, Irwan Akib, Muhammad Muzaini
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Effective Reading Interventions for Slow Learners : Sight Word and Phonemic Awareness Approaches

open access: yesJurnal Paedagogy
This study investigates the effectiveness of sight words and phonemic awareness learning, delivered through drilling method, in enhancing reading skills in a child identified as slow learner.
Jihan Salsabila Purnomo   +1 more
doaj   +1 more source

A study on the impact of social skill Training on social adjustment and academic performance in slow learners [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2010
The present study was designed to investigate the impact of social skill training on social adjustment and academic performance in slow learners. For this purpose, 50 male slow learners in second grade of primary schools in Khodabandeh (a city of Zanjan ...
Ahmad Beh-Pajooh   +3 more
doaj  

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