Results 231 to 240 of about 543,226 (367)

Caspase 8 small interfering RNA prevents acute liver failure in mice

, 2003
Lars Zender, Sebastian Hütker, Christian Liedtke, Hans L. Tillmann, Steffen Zender, Bettina Mundt, M Waltemathe, Thomas Gösling, Peer Flemming, Nisar P. Malek, Christian Trautwein, Michael P. Manns, Florian Kühnel, Stefan Kubicka   +13 more
openalex   +1 more source

Gene Profiling of Cottontail Rabbit Papillomavirus-Induced Carcinomas Identifies Upregulated Genes Directly Involved in Stroma Invasion as Shown by Small Interfering RNA-Mediated Gene Silencing [PDF]

, 2004
Evamaria Huber, Daniela Vlasny, Sonja Jeckel, Frank Stubenrauch, Thomas Iftner   +4 more
openalex   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

Small Interfering RNA Therapy for the Management and Prevention of Hypertension. [PDF]

Curr Hypertens Rep
Ren L, Danser AHJ.
europepmc   +1 more source

Silver Nanoparticles Modified by Carbosilane Dendrons and PEG as Delivery Vectors of Small Interfering RNA. [PDF]

Int J Mol Sci, 2023
Abashkin V, Pędziwiatr-Werbicka E, Horodecka K, Zhogla V, Ulashchik E, Shmanai V, Shcharbin D, Bryszewska M.   +7 more
europepmc   +1 more source

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

, 2003
Zhen Jiang, Qiong Zhou, Kerri Ann Coleman, My Chouinard, Queta Boese, Michael Czech   +5 more
openalex   +1 more source

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

Advanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu, Shuai Zhou, Tingting Zou, Guangzhao Hou, Qian Xiao, Lin Li, Jianjun Yang, Wei Chen, Yingze Zhang, Hongzhi Lv   +9 more
wiley   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Clay nanoparticles efficiently deliver small interfering RNA to intact plant leaf cells. [PDF]

Plant Physiol, 2022
Yong J, Wu M, Zhang R, Bi S, Mann CWG, Mitter N, Carroll BJ, Xu ZP.   +7 more
europepmc   +1 more source

Stable expression of small interfering RNA sensitizes TEL-PDGFβR to inhibition with imatinib or rapamycin [PDF]

, 2004
Jing Chen, Nathan R. Wall, Kerry Kocher, Nicole Duclos, Doriano Fabbro, Donna Neuberg, James D. Griffin, Yang Shi, D. Gary Gilliland   +8 more
openalex   +1 more source