Results 241 to 250 of about 543,226 (367)

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Use of adeno-associated viral vector for delivery of small interfering RNA

, 2003
Raghuvir Singh Tomar, Hittu Matta, Preet M. Chaudhary   +2 more
openalex   +1 more source

Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in vivo. [PDF]

, 2004
Marion A. Flynn, David Casey, Stephen Todryk, Bernard P. Mahon   +3 more
openalex   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

Unveiling the intricacies: small interfering RNA targeting Snail-1 unravels dynamics in endometrial carcinoma cell behavior. [PDF]

Front Oncol
Li F, Zhi Y, Wang Y, Hussain SA, Alrubie TM, Yang P.   +5 more
europepmc   +1 more source

Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy. [PDF]

Mol Ther Nucleic Acids, 2023
Lin L, Zhu S, Huang H, Wu LP, Huang J.
europepmc   +1 more source

Double transfection improves small interfering RNA‐induced thrombin receptor (PAR‐1) gene silencing in DU 145 prostate cancer cells [PDF]

, 2004
Jian Liu, P. Schuff‐Werner, Michael Steiner   +2 more
openalex   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Targeted knockdown of canine KIT (stem cell factor receptor) using small interfering RNA [PDF]

, 2010
Argyle, D., Catchpole, B., Elders, Richard, Holder, A.   +3 more
core  

Silencing Expression of the Clusterin/Apolipoprotein J Gene in Human Cancer Cells Using Small Interfering RNA Induces Spontaneous Apoptosis, Reduced Growth Ability, and Cell Sensitization to Genotoxic and Oxidative Stress [PDF]

, 2004
Ioannis P. Trougakos, Alan So, Burkhard Jansen, Martin Gleave, Efstathios S. Gonos   +4 more
openalex   +1 more source