Results 311 to 320 of about 544,838 (323)

The Efficacy and Safety of Polyethylene Glycol Cholesterol- and Tocopherol Polyethylene Glycol 1000 Succinate-Modified Transforming Growth Factor β1 Small Interfering RNA Lipid Nanoparticles in the Treatment of Paclitaxel-Resistant Non-Small-Cell Lung Cancer. [PDF]

Pharmaceutics
Zeng Z, Zeng X, Li X, Feng Y, Kan Y, Liu X, Zeng Y.   +6 more
europepmc   +1 more source

Functional inhibition of the p75 receptor using a small interfering RNA [PDF]

ヒグチ, ハルヒサ, 樋口, 晴久
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Self‐Catalytic Small Interfering RNA Nanocarriers for Synergistic Treatment of Neurodegenerative Diseases

Advances in Materials, 2021
Gene therapy has shown great potential for neurodegenerative diseases with complex pathology. However, its therapeutic effect is limited due to the delivery barriers and its own single function.
Weihong Ji, Yan Li, Huan Peng, Ruichen Zhao, Jie Shen, Yanyue Wu, Jianze Wang, Qiulian Hao, Zhiguo Lu, Jun Yang, Xin Zhang   +10 more
semanticscholar   +1 more source

Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages.

ACS Nano, 2017
Tumor-associated macrophages (TAMs) are a promising therapeutic target for cancer immunotherapy. Targeted delivery of therapeutic drugs to the tumor-promoting M2-like TAMs is challenging. Here, we developed M2-like TAM dual-targeting nanoparticles (M2NPs)
Yuan Qian, Sha Qiao, Yanfeng Dai, Guoqiang Xu, Bolei Dai, Lisen Lu, Xiang Yu, Qingming Luo, Zhihong Zhang   +8 more
semanticscholar   +1 more source

Small Interfering RNA in Milk Exosomes Is Resistant to Digestion and Crosses the Intestinal Barrier In Vitro.

Journal of Agricultural and Food Chemistry, 2017
Milk is not only a composite of nutrients but emerged as a source of exosomes acting as a promising drug delivery vehicle for small interfering RNA (siRNA).
Shruti Shandilya, Payal Rani, S. Onteru, Dheer Singh   +3 more
semanticscholar   +1 more source

Photocaged Small Interfering RNA

Russian journal of bioorganic chemistry, 2022
E. Akhmetova, D. V. Kim, A. Dome, M. Meschaninova, D. Novopashina   +4 more
semanticscholar   +1 more source

Small Interfering RNA Therapeutic Inclisiran: A New Approach to Targeting PCSK9

BioDrugs, 2019
C. German, M. Shapiro
semanticscholar   +1 more source

Effective expression of small interfering RNA in human cells

Nature Biotechnology, 2002
C. P. Paul, P. Good, Ira Winer, D. Engelke   +3 more
semanticscholar   +1 more source

Cypate‐Conjugated Porous Upconversion Nanocomposites for Programmed Delivery of Heat Shock Protein 70 Small Interfering RNA for Gene Silencing and Photothermal Ablation

, 2016
Lu Wang, C. Gao, Keyin Liu, Yuxin Liu, Liyi Ma, Lidong Liu, Xiaoxia Du, Jing Zhou   +7 more
semanticscholar   +1 more source