Systematic mapping of small nucleolar RNA interactions in human cells [PDF]
RNA BiologyAltered expression of box C/D small nucleolar RNAs (snoRNAs) is implicated in human diseases, including cancer. Box C/D snoRNAs canonically direct site-specific, 2’-O-methylation but the extent to which they participate in other functions remains unclear.
Hywel Dunn-Davies +5 more
doaj +3 more sources
Characterization of small nucleolar RNA retaining transcripts in human normal and cancer cells [PDF]
Non-coding RNA ResearchSmall nucleolar RNAs are non-coding RNAs typically encoded within the introns of both protein-coding and non-coding genes. Interestingly, a significant fraction of snoRNA sequences is found as retained introns of specific mRNA isoforms expressed from ...
Guglielmo Rambaldelli +10 more
doaj +3 more sources
Enabling factor for cancer hallmark acquisition: Small nucleolar RNA host gene 17 [PDF]
Frontiers in Oncology, 2022 The role of long non-coding RNA (lncRNA) in human tumors has gradually received increasing attention in recent years. Particularly, the different functions of lncRNAs in different subcellular localizations have been widely investigated.
Ningzhi Zhang +4 more
doaj +3 more sources
Systematic pan-cancer analysis on the expression and role of regulator of chromatin condensation 1/small nucleolar RNA host gene 3/small nucleolar RNA host gene 12 [PDF]
Frontiers in Molecular Biosciences, 2022 Regulator of chromatin condensation 1 (RCC1) is the major guanine nucleotide exchange factor of RAN GTPase, which plays a key role in various biological processes such as cell cycle and DNA damage repair. Small nucleolar RNA host gene 3 (SNHG3) and small
Kai Hu +4 more
doaj +2 more sources
Small but strong: the emerging role of small nucleolar RNA in cardiovascular diseases [PDF]
Frontiers in Cell and Developmental Biology, 2023 Cardiovascular diseases (CVDs) are the leading cause of mortality and disability worldwide. Numerous studies have demonstrated that non-coding RNAs (ncRNAs) play a primary role in CVD development.
Xue Sun +11 more
doaj +2 more sources
Small Nucleolar RNA from S. cerevisiae Binds to Phosphatidylinositol 4,5-Bisphosphate [PDF]
Non-Coding RNABackground: snoRNAs have traditionally been known for their role as guides in post-transcriptional rRNA modifications. Previously, our research group identified several RNAs that may bind to PIP2 with LIPRNA-seq.
Irma A. Jiménez-Ramírez +3 more
doaj +2 more sources
Small nucleolar RNA dysregulation and potential roles in bovine subclinical mastitis [PDF]
Journal of Animal Science and BiotechnologyBackground Subclinical mastitis, caused by many pathogens including Staphylococcus aureus (S. aureus) and Staphylococcus chromogenes (S. chromogenes), presents a major challenge to the dairy industry due to its associated economic losses and poor milk ...
Faith A. Omonijo +6 more
doaj +2 more sources
U8 variants on the brain: a small nucleolar RNA and human disease [PDF]
RNA Biology, 2022 Small nucleolar RNAs (snoRNAs) are non-coding RNAs vital for ribosomal RNA (rRNA) maturation. The U8 snoRNA, encoded by the SNORD118 gene in humans, is an atypical C/D box snoRNA as it promotes rRNA cleavage rather than 2′–O–methylation and is unique to ...
Emily J. McFadden, Susan J. Baserga
doaj +2 more sources
LncRNA small nucleolar RNA host gene 1 (SNHG1) mediates acidic bile salt-induced EMT via the ULK1-Notch1 axis in Barrett's esophagus. [PDF]
Mol BiomedZhou J +8 more
europepmc +3 more sources
Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression. [PDF]
Funct Integr GenomicsZhang L +8 more
europepmc +3 more sources