Results 111 to 120 of about 442,180 (329)

Integrated analysis reveals a potential cuproptosis-related ceRNA axis SNHG17/miR-29a-3p/GCSH in prostate adenocarcinoma

open access: yesHeliyon, 2023
Cuproptosis is a novel form of programmed cell death. The role and mechanism of cuproptosis-related genes in prostate adenocarcinoma have not been fully understood. In this study, a series of bioinformatic analyses were performed.
Shuyuan Xiao, Weiyang Lou
doaj  

Small Nucleolar RNA Host Gene 18 Acts as a Tumor Suppressor and a Diagnostic Indicator in Hepatocellular Carcinoma

open access: yesTechnology in Cancer Research and Treatment, 2018
Background: Noncoding RNAs are crucial regulators acting as either tumor suppressor genes or oncogenes in human cancer progression. The aberrant expression of noncoding RNAs has been confirmed in different kinds of cancers.
Xuefang Liu   +7 more
semanticscholar   +1 more source

Noncoding RNAs in Host–Microbiota Interaction

open access: yesAnimal Research and One Health, EarlyView.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao   +7 more
wiley   +1 more source

C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Small nucleolar RNAs (snoRNAs) play an important role in carcinogenesis. In this study, we identified a C/D box snoRNA, snord105b, and further investigated the function and mechanism of the snord105b in gastric cancer (GC).
Cong Zhang   +6 more
doaj   +1 more source

Engineered Ripening-Specific Accumulation of Polyamines Spermidine and Spermine in Tomato Fruit Upregulates Clustered C/D Box snoRNA Gene Transcripts in Concert with Ribosomal RNA Biogenesis in the Red Ripe Fruit

open access: yesPlants, 2020
Ripening of tomato fruit leads, in general, to a sequential decrease in the endogenous levels of polyamines spermidine (SPD) and spermine (SPM), while the trend for the diamine putrescine (PUT) levels is generally an initial decrease, followed by a ...
Vijaya Shukla   +4 more
doaj   +1 more source

Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

open access: yesChemBioChem, Accepted Article.
Nucleophosmin 1(NPM1) is an abundant human protein endowed with many functions whose dysregulation leads to various cancers and mutations are relevant in Acute Myeloid Leukemia (AML). In the wild type form, pentameric NPM1 resides mainly in the nucleolus even if it shuttles toward the cytosol exerting its chaperon function, conversely in AML‐mutated ...
Daniele Florio   +7 more
wiley   +1 more source

Molecular Mechanisms and Clinical Implications of Noncoding RNAs in Cancer

open access: yesNon-Coding RNA
Noncoding RNAs (ncRNAs), which include small nuclear RNAs (snRNAs), small nucleolar RNAs (snoRNAs), microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), are RNA molecules that arise from genomic regions without protein-coding ...
Jin Wang, Xiaomeng He, Christopher Corpe
doaj   +1 more source

RNA-Based Liquid Biopsy in Head and Neck Cancer

open access: yesCells, 2023
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial for improving patient outcomes.
Jacek Kabzinski   +2 more
doaj   +1 more source

Radial distribution of RNA genome packaged inside spherical viruses [PDF]

open access: yes, 2008
The problem of RNA genomes packaged inside spherical viruses is studied. The viral capsid is modeled as a hollowed sphere. The attraction between RNA molecules and the inner viral capsid is assumed to be non-specific and occurs at the inner capsid surface only.
arxiv   +1 more source

H/ACA box small nucleolar RNA 7B acts as an oncogene and a potential prognostic biomarker in breast cancer

open access: yesCancer Cell International, 2019
Breast cancer (BC) is the most frequent malignancy occurring in women worldwide. Emerging evidence indicates that small nucleolar RNAs (snoRNAs) play a role in tumor development.
Yihan Sun   +7 more
semanticscholar   +1 more source

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