Results 31 to 40 of about 202,981 (234)
On the nucleolar size and density in human early granulocytic progenitors, myeloblasts
European Journal of Histochemistry, 2009 Human myeloblasts were studied in bone marrow of patients suffering from chronic phase of chronic myeloid leukaemia to provide more information on the nucleolar diameter in these early granulocytic progenitors. These cells are a convenient model for such
K Smetana +4 more
doaj +1 more source
Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
Nature Communications, 2020 Small non-coding RNAs contribute to the regulation of aging. Here the authors identify a small nucleolar RNA, the snoRNA jouvence, which extends the lifespan of fruit flies through its function in the gut, and is conserved in humans.
Stéphanie Soulé +4 more
doaj +1 more source
Medical Science Monitor, 2019 Background Long noncoding RNAs (lncRNAs) play important roles in cancer development and therapeutic resistance. However, the role of small nucleolar RNA host gene 16 (SNHG16) in the development of hepatocellular carcinoma (HCC) remains largely unknown ...
Zhenli Guo +6 more
semanticscholar +1 more source
Cell Reports, 2017 Non-coding RNA biogenesis in higher eukaryotes has not been fully characterized. Here, we studied the Drosophila melanogaster Rexo5 (CG8368) protein, a metazoan-specific member of the DEDDh 3′-5′ single-stranded RNA exonucleases, by genetic, biochemical,
Stefanie Gerstberger +8 more
doaj +1 more source
Open Life Sciences, 2020 Osteosarcoma is a common primary malignant bone cancer. Long noncoding RNA small nucleolar RNA host gene 15 (SNHG15) has been reported to play an oncogenic role in many cancers.
Zhang Jinshan +5 more
doaj +1 more source
SnoRNA and lncSNHG: Advances of nucleolar small RNA host gene transcripts in anti-tumor immunity
Frontiers in Immunology, 2023 The small nucleolar RNA host genes (SNHGs) are a group of genes that can be transcript into long non-coding RNA SNHG (lncSNHG) and further processed into small nucleolar RNAs (snoRNAs).
Hao Xiao +9 more
doaj +1 more source
Journal of Breast Cancer, 2019 Purpose Recent studies have shown that long non-coding RNA (lncRNA) play an important role in cancer metabolism and development. The lncRNA small nucleolar RNA host gene 7 (SNHG7) was reported to be upregulated in colorectal cancer and contribute to its ...
Linlei Zhang, Yanying Fu, Hao Guo
semanticscholar +1 more source
RNA-Seq of the nucleolus reveals abundant SNORD44-derived small RNAs. [PDF]
PLoS ONE, 2014 Small non-coding RNAs represent RNA species that are not translated to proteins, but which have diverse and broad functional activities in physiological and pathophysiological states. The knowledge of these small RNAs is rapidly expanding in part through
Baoyan Bai +3 more
doaj +1 more source
Cancer Medicine, 2020 The main purpose of the present study is to screen prognostic small nucleolar RNA (snoRNA) markers using the RNA‐sequencing (RNA‐seq) dataset of The Cancer Genome Atlas (TCGA) sarcoma cohort.
Jianwei Liu +4 more
semanticscholar +1 more source
The genetic and pharmacogenomic landscape of snoRNAs in human cancer
Molecular Cancer, 2020 Emerging evidence has revealed significant roles for small nucleolar RNAs (snoRNAs) in tumorigenesis. However, the genetic and pharmacogenomic landscape of snoRNAs has not been characterized.
Yaoming Liu +10 more
doaj +1 more source