Results 51 to 60 of about 442,180 (329)
RNA regulation of lipotoxicity and metabolic stress [PDF]
, 2016 Noncoding RNAs are an emerging class of nonpeptide regulators of metabolism. Metabolic diseases and the altered metabolic environment induce marked changes in levels of microRNAs and long noncoding RNAs.
Caputa, George, Schaffer, Jean E
core +2 more sources
On the nucleolar size and density in human early granulocytic progenitors, myeloblasts
European Journal of Histochemistry, 2009 Human myeloblasts were studied in bone marrow of patients suffering from chronic phase of chronic myeloid leukaemia to provide more information on the nucleolar diameter in these early granulocytic progenitors. These cells are a convenient model for such
K Smetana +4 more
doaj +1 more source
Medical Science Monitor, 2019 Background Long noncoding RNAs (lncRNAs) play important roles in cancer development and therapeutic resistance. However, the role of small nucleolar RNA host gene 16 (SNHG16) in the development of hepatocellular carcinoma (HCC) remains largely unknown ...
Zhenli Guo +6 more
semanticscholar +1 more source
Characterization of a novel trypanosomatid small nucleolar RNA [PDF]
Nucleic Acids Research, 1998 Trypanosomes possess unique RNA processing mechanisms including trans- splicing of pre-mRNA and RNA editing of mitochondrial transcripts. The previous finding of a trimethylguanosine (TMG) capped U3 homologue in trypanosomes suggests that rRNA processing may be related to the processing in other eukaryotes.
Alexander Levitan +5 more
openaire +3 more sources
Open Life Sciences, 2020 Osteosarcoma is a common primary malignant bone cancer. Long noncoding RNA small nucleolar RNA host gene 15 (SNHG15) has been reported to play an oncogenic role in many cancers.
Zhang Jinshan +5 more
doaj +1 more source
Deep Learning-Based Automatic Assessment of AgNOR-scores in Histopathology Images [PDF]
arXiv, 2022 Nucleolar organizer regions (NORs) are parts of the DNA that are involved in RNA transcription. Due to the silver affinity of associated proteins, argyrophilic NORs (AgNORs) can be visualized using silver-based staining. The average number of AgNORs per nucleus has been shown to be a prognostic factor for predicting the outcome of many tumors.
arxiv
Journal of Breast Cancer, 2019 Purpose Recent studies have shown that long non-coding RNA (lncRNA) play an important role in cancer metabolism and development. The lncRNA small nucleolar RNA host gene 7 (SNHG7) was reported to be upregulated in colorectal cancer and contribute to its ...
Linlei Zhang, Yanying Fu, Hao Guo
semanticscholar +1 more source
Characterization of a second open reading frame in genome segment 10 of bluetongue virus [PDF]
, 2015 Viruses have often evolved overlapping reading frames in order to maximise their coding capacity. Until recently, the segmented double-stranded (ds) RNA genome of viruses of the Orbivirus genus was thought to be monocistronic but the identification of ...
Barry, Gerald +11 more
core +2 more sources
Cell Reports, 2017 Non-coding RNA biogenesis in higher eukaryotes has not been fully characterized. Here, we studied the Drosophila melanogaster Rexo5 (CG8368) protein, a metazoan-specific member of the DEDDh 3′-5′ single-stranded RNA exonucleases, by genetic, biochemical,
Stefanie Gerstberger +8 more
doaj +1 more source
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis
Nature Communications, 2021 Lipid induced stress contributes to metabolic diseases. Here the authors identify small nucleolar RNA 73 (SNORA73) in a screen for genes that protect against lipotoxicity and show that deficiency of SNORA73 reprograms oxidative metabolism and protects ...
Arthur C. Sletten +13 more
doaj +1 more source