A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB +6 more
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West Africa Smallpox/Measles Control Probram surveillance report [PDF]
Smallpox and yellow fever in West and West-Central Africa, 1940-1965: The tables and figures presented in this section of the Surveillance Report represent the best data available to the Smallpox Eradication Program at the present time regarding yellow ...
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Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan. [PDF]
Pharmacol Res PerspectABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Akinbolade S +5 more
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The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Genome Biology, 2020 Vaccination has transformed public health, most notably including the eradication of smallpox. Despite its profound historical importance, little is known of the origins and diversity of the viruses used in smallpox vaccination.
Ana T. Duggan +21 more
doaj +1 more source
Smallpox, Monkeypox and Other Human Orthopoxvirus Infections
Viruses, 2022 Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all ...
Galina A. Shchelkunova +1 more
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Remaining Questions about Clinical Variola Major
Emerging Infectious Diseases, 2011 After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
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Progression of pathogenic events in cynomolgus macaques infected with variola virus. [PDF]
PLoS ONE, 2011 Smallpox, caused by variola virus (VARV), is a devastating human disease that affected millions worldwide until the virus was eradicated in the 1970 s.
Victoria Wahl-Jensen +10 more
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The rediscovery of smallpox [PDF]
Clinical Microbiology and Infection, 2014 Smallpox is an infectious disease that is unique to humans, caused by a poxvirus. It is one of the most lethal of diseases; the virus variant Variola major has a mortality rate of 30%. People surviving this disease have life-long consequences, but also assured immunity. Historically, smallpox was recognized early in human populations.
Thèves, Catherine +2 more
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Contingency planning for a deliberate release of smallpox in Great Britain : the role of geographical scale and contact structure [PDF]
, 2010 Background: In the event of a release of a pathogen such as smallpox, which is human-to-human transmissible and has high associated mortality, a key question is how best to deploy containment and control strategies.
Hall, Ian +11 more
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