Results 21 to 30 of about 45,583 (234)

Phase-out of smallpox vaccination and the female/male HIV-1 prevalence ratio: an ecological study from Guinea-Bissau

open access: yesBMJ Open, 2019
Objective In Guinea-Bissau, West Africa, we observed that having a smallpox vaccination scar was associated with lower HIV-1 prevalence, more strongly for women than men.
Marie Villumsen   +8 more
doaj   +1 more source

Patterns of smallpox mortality in London, England, over three centuries.

open access: yesPLoS Biology, 2020
Smallpox is unique among infectious diseases in the degree to which it devastated human populations, its long history of control interventions, and the fact that it has been successfully eradicated.
Olga Krylova, David J D Earn
doaj   +1 more source

Reflections on Dr J Michael Lane, a giant of public health (1936-2020)

open access: yesGlobal Biosecurity, 2020
Reflections on Dr J Michael Lane (1936-2020) a global leader in smallpox eradication and the Director of Smallpox Eradication at the US CDC. Dr Lane was an alumnus of the US CDC's Epidemic Intelligence Service and had worked in global health on control ...
C Raina MacIntyre
doaj   +1 more source

Efficacy of CMX001 as a Prophylactic and Presymptomatic Antiviral Agent in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

open access: yesViruses, 2011
CMX001, a lipophilic nucleotide analog formed by covalently linking 3‑(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox.
Richard W. Moyer   +7 more
doaj   +1 more source

Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks

open access: yesHealth Science Reports, 2022
Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam   +6 more
doaj   +1 more source

Following in the footsteps of smallpox: can we achieve the global eradication of measles? [PDF]

open access: yes, 2004
BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths.
Morgan Oliver WC   +2 more
core   +1 more source

Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence

open access: yesEmerging Infectious Diseases, 2018
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre   +7 more
doaj   +1 more source

Low-Temperature Multiple Micro-Dispensing on Microneedles for Accurate Transcutaneous Smallpox Vaccination

open access: yesVaccines, 2022
Smallpox is an acute contagious disease caused by the variola virus. According to WHO guidelines, the smallpox vaccine is administrated by scarification into the epidermis using a bifurcated needle moistened with a vaccine solution.
Sang-Gu Yim   +11 more
doaj   +1 more source

Eczema Herpeticum and Clinical Criteria for Investigating Smallpox

open access: yesEmerging Infectious Diseases, 2009
Eczema herpeticum can clinically resemble smallpox. On the basis of the algorithm for rapid evaluation of patients with an acute generalized vesiculopustular rash illness, our patient met criteria for high risk for smallpox.
David A. Boyd   +2 more
doaj   +1 more source

Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus.

open access: yesPLoS Pathogens, 2021
Smallpox, caused by the solely human pathogen Variola virus (VARV), was declared eradicated in 1980. While known VARV stocks are secure, smallpox remains a bioterrorist threat agent. Recent U.S. Food and Drug Administration approval of the first smallpox
Christina L Hutson   +13 more
doaj   +1 more source

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