Results 21 to 30 of about 14,512 (186)
Acute Late-Stage Myocarditis in the Crab-Eating Macaque Model of Hemorrhagic Smallpox
Viruses, 2021 Hemorrhagic smallpox, caused by variola virus (VARV), was a rare but nearly 100% lethal human disease manifestation. Hemorrhagic smallpox is frequently characterized by secondary bacterial infection, coagulopathy, and myocardial and subendocardial ...
Reed F. Johnson +19 more
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The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Genome Biology, 2020 Vaccination has transformed public health, most notably including the eradication of smallpox. Despite its profound historical importance, little is known of the origins and diversity of the viruses used in smallpox vaccination.
Ana T. Duggan +21 more
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Smallpox, Monkeypox and Other Human Orthopoxvirus Infections
Viruses, 2022 Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all ...
Galina A. Shchelkunova +1 more
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Remaining Questions about Clinical Variola Major
Emerging Infectious Diseases, 2011 After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
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Progression of pathogenic events in cynomolgus macaques infected with variola virus. [PDF]
PLoS ONE, 2011 Smallpox, caused by variola virus (VARV), is a devastating human disease that affected millions worldwide until the virus was eradicated in the 1970 s.
Victoria Wahl-Jensen +10 more
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The rediscovery of smallpox [PDF]
Clinical Microbiology and Infection, 2014 Smallpox is an infectious disease that is unique to humans, caused by a poxvirus. It is one of the most lethal of diseases; the virus variant Variola major has a mortality rate of 30%. People surviving this disease have life-long consequences, but also assured immunity. Historically, smallpox was recognized early in human populations.
Thèves, Catherine +2 more
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Contingency planning for a deliberate release of smallpox in Great Britain : the role of geographical scale and contact structure [PDF]
, 2010 Background: In the event of a release of a pathogen such as smallpox, which is human-to-human transmissible and has high associated mortality, a key question is how best to deploy containment and control strategies.
Hall, Ian +11 more
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Patterns of smallpox mortality in London, England, over three centuries.
PLoS Biology, 2020 Smallpox is unique among infectious diseases in the degree to which it devastated human populations, its long history of control interventions, and the fact that it has been successfully eradicated.
Olga Krylova, David J D Earn
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Reflections on Dr J Michael Lane, a giant of public health (1936-2020)
Global Biosecurity, 2020 Reflections on Dr J Michael Lane (1936-2020) a global leader in smallpox eradication and the Director of Smallpox Eradication at the US CDC. Dr Lane was an alumnus of the US CDC's Epidemic Intelligence Service and had worked in global health on control ...
C Raina MacIntyre
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