Results 51 to 60 of about 125,699 (320)
Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial [PDF]
BackgroundModified Vaccinia Ankara (MVA) is a live, viral vaccine under advanced development as a non-replicating smallpox vaccine. A randomised, double-blind, placebo-controlled phase III clinical trial was conducted to demonstrate the humoral ...
Chaplin, Paul+12 more
core +3 more sources
Smallpox is an acute contagious disease caused by the variola virus. According to WHO guidelines, the smallpox vaccine is administrated by scarification into the epidermis using a bifurcated needle moistened with a vaccine solution.
Sang-Gu Yim+11 more
doaj +1 more source
Evolution of means and principles of smallpox vaccination
There are several possible reasons for the return of smallpox as an endemic disease. For example, the possibility of maintaining smallpox virus in an active state in the corpses of the dead, buried in permafrost regions, or the evolutionary changes of ...
S. V. Borisevich+7 more
doaj +1 more source
Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus.
Smallpox, caused by the solely human pathogen Variola virus (VARV), was declared eradicated in 1980. While known VARV stocks are secure, smallpox remains a bioterrorist threat agent. Recent U.S. Food and Drug Administration approval of the first smallpox
Christina L Hutson+13 more
doaj +1 more source
Unifying incidence and prevalence under a time-varying general branching process [PDF]
Renewal equations are a popular approach used in modelling the number of new infections, i.e., incidence, in an outbreak. We develop a stochastic model of an outbreak based on a time-varying variant of the Crump-Mode-Jagers branching process. This model accommodates a time-varying reproduction number and a time-varying distribution for the generation ...
arxiv
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Monkeypox is a smallpox-like illness that can be accompanied by a range of significant medical complications. To date there are no standard or optimized guidelines for the clinical management of monkeypox (MPX) patients, particularly in low-resource ...
M. Reynolds+4 more
semanticscholar +1 more source
Contains fulltext : 190586.pdf (publisher's version ) (Open Access)20 ...
Devos, Isabelle, Janssens, Angélique
core +2 more sources
Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj +1 more source
In vitro micropropagation and apocarotenoid gene expression in saffron [PDF]
Saffron (Crocus sativus L.) is a triploid, sterile, monocot plant belonging to the family Iridaceae, sub-family Crocoideae. C.sativus only blooms once a year and should be collected within a very short duration, the stigmas of Saffron flowers are harvested manually and subjected to desiccation then have been used as a spice.
arxiv