Results 51 to 60 of about 112,363 (272)

Global perspectives on smallpox vaccine against monkeypox: a comprehensive meta-analysis and systematic review of effectiveness, protection, safety and cross-immunogenicity

open access: yesEmerging Microbes and Infections
A large outbreak of monkeypox occurred in 2022, and most people lack immunity to orthopoxvirus. Smallpox vaccination is essential for preventing further smallpox outbreaks.
Hao Liu   +7 more
doaj   +1 more source

Evolution of means and principles of smallpox vaccination

open access: yesВестник войск РХБ защиты, 2020
There are several possible reasons for the return of smallpox as an endemic disease. For example, the possibility of maintaining smallpox virus in an active state in the corpses of the dead, buried in permafrost regions, or the evolutionary changes of ...
S. V. Borisevich   +7 more
doaj   +1 more source

Following in the footsteps of smallpox: can we achieve the global eradication of measles? [PDF]

open access: yes, 2004
BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths.
Morgan, Oliver WC
core   +2 more sources

Accelerating Enzyme Engineering With Artificial Intelligence in Biocatalysis: Challenges and Opportunities

open access: yesFood Bioengineering, EarlyView.
ABSTRACT Artificial intelligence (AI) has emerged as a paradigm‐shifting force in enzyme engineering, enabling data‐driven prediction of catalytic activity, stability, and substrate specificity. By integrating large‐scale datasets from structured databases (e.g., PDB, BRENDA) and high‐throughput experimentation (e.g., deep mutational scanning ...
Xiafeng Lu   +11 more
wiley   +1 more source

Rethinking the History of Smallpox in the Early Twentieth Century: The and Uncertainty Surrounding the Diagnosis of Smallpox [PDF]

open access: yesUisahak, 2020
This research explores the case of the 1903 smallpox outbreak on the SS Korea, a transpacific carrier making runs between Southeast Asia, East Asia, Hawaii, and the United States.
Hyon Ju LEE
doaj   +1 more source

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections

open access: yesViruses, 2010
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj   +1 more source

Effect of Monkeypox Virus Preparation on the Lethality of the Intravenous Cynomolgus Macaque Model

open access: yesViruses, 2022
For over two decades, researchers have sought to improve smallpox vaccines and also develop therapies to ensure protection against smallpox or smallpox-like disease.
Eric M. Mucker   +5 more
doaj   +1 more source

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Mpox is a zoonotic viral infection caused by monkeypox virus (MPXV) and risk factors for its dissemination include previous dermatoses such as atopic dermatitis [1]. We present the case of a 30‐year‐old male with an unusual and extensive presentation of mpox following unprotected sexual intercourse, with an excellent response to tecovirimat ...
Andrés Vidal González   +6 more
wiley   +1 more source

We should be prepared to smallpox re-emergence

open access: yesВопросы вирусологии, 2019
The review contains a brief analysis of the results of investigations conducted during 40 years after smallpox eradication and directed to study genomic organization and evolution of variola virus (VARV) and development of modern diagnostics, vaccines ...
S. N. Shchelkunov, G. A. Shchelkunova
doaj   +1 more source

Navigating the smallpox threat in colonial Fiji: Vaccination endeavours and historical challenges

open access: yesCogent Arts & Humanities, 2023
Upon its cession from 1874 to 1970, Fiji was under the British colonial government, and the colonial government attempted to control the spread of smallpox in the colony.
Mumtaz Alam
doaj   +1 more source

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